Zorex - antidote; a donor of sulfhydryl (thiol) groups with a detoxification effect, including with respect to arsenic compounds, heavy metals and their compounds, as well as half-life products of ethanol.
Release form and composition
Zorex is available in two types of gelatin capsules.
The concentration of active substances in the preparation:
- Capsules No. 0 - 150 mg of sodium dimercaptopropanesulfonate (unithiol) and 7 mg of calcium pantothenate;
- Capsules №00 - 250 mg of unithiol and 10 mg of calcium pantothenate.
Auxiliary components of both types of capsules are: povidone, pregelatinized starch, magnesium hydrogen phosphate trihydrate, colloidal silicon dioxide, microcrystalline cellulose, citric acid.
The body of the capsule is made of gelatin and titanium dioxide with the addition of dye azorubin (E122).
Zorex capsules packaged in blisters are sold:
- Capsules number 0 - 10 pcs .;
- Capsules number 00 - 2 and 5 pcs.
Indications for use
Zorex is taken to prevent and eliminate alcohol withdrawal syndrome (hangover).
In addition, the drug is used to treat:
- Intoxication with cardiac glycosides;
- Acute and chronic poisoning with inorganic and organic compounds of arsenic, mercury, gold, chromium, cobalt, zinc, chromium, bismuth, cadmium, antimony, nickel.
As part of complex therapy, Zorex is prescribed in the treatment of chronic alcoholism.
Zorek can not be taken:
- Children and teenagers under 18;
- Patients with severe liver or kidney disease in the stage of decompensation;
- In the presence of hypersensitivity to any component of the drug.
It is not recommended to take Zorex also for pregnant and lactating women, as the data on the safety of its use during these periods is not enough.
With extreme caution, the drug is used with low blood pressure.
Dosing and Administration
Take Zorex should be 30 minutes before a meal, squeezed water.
In case of alcohol withdrawal, 1 capsule №00 (250 + 10 mg) is administered 1-2 times per day. In some cases, the multiplicity of techniques can be increased up to 3 times. The duration of Zorex is determined by the moment of disappearance of the symptoms of intoxication. As a rule, it takes from 3 to 7 days.
In chronic alcoholism, Zorex is taken 1-2 times a day, 1 capsule No. 0 (150 + 7 mg). The course of treatment is usually 10 days.
In case of various types of poisoning, depending on the degree of intoxication, the drug is prescribed in a daily dose of 300-1000 mg (according to unithiol), divided into 2-3 doses. In this case, the duration of treatment is 7-10 days.
Zorex can also be taken to prevent a hangover. To do this, on the day of alcohol intake at bedtime, take one capsule No. 00.
The drug is generally well tolerated. However, in case of hypersensitivity to any active or auxiliary component, allergic reactions may develop, manifested by a rash on the skin and mucous membranes, itching, hives, stomatitis, genital itching. In rare cases, more serious reactions such as angioedema and Stephen-Johnson syndrome occur.
When you take Zorex in high doses, sometimes nausea, dizziness, tachycardia, paleness of the skin.
With an overdose of Zorex (if the recommended dose is exceeded 10 times or more), short-term seizures, shortness of breath, hyperkinesis, stunnedness, lethargy, inhibition are possible. If the patient has taken a too high dose of the drug, it is necessary to do a gastric lavage, take activated charcoal and a laxative. In more severe cases, oxygen therapy (the use of oxygen for therapeutic purposes) and the introduction of dextrose may be required. The complementary treatment of overdose is symptomatic.
The risk of developing an allergy to the drug is significantly increased in patients with bronchial asthma and in people with allergies in the anamnesis.
Zorex is pharmacologically incompatible with preparations containing heavy metal salts and alkalis.
The drug does not have a negative effect on the reaction rate, visual acuity and ability to concentrate; therefore it can be used by people of any profession.
Unithiol, R-X 1.
Terms and conditions of storage
Capsules should be stored in their original packaging in a dark, dry place at a temperature of 10-25 ºС. Shelf life Zorex - 2 years.