Zaditen refers to antihistamine drugs of systemic action.
Release form and composition
Zaditen is available in the following dosage forms:
- Tablets containing 1 mg of ketotifen (in the form of hydrogen fumarate) and excipients (lactose monohydrate, magnesium stearate, corn starch). One pack contains 30 tablets of white, grayish-white or yellowish-white color;
- Syrup for children, in 5 ml of which contains 1 ml of ketotifen (in the form of hydrogen fumarate). It is sold in bottles of 100 ml;
- Eye drops, 1 ml of which contains 250 μg of ketotifen. Available in bottles of 5 ml.
Indications for use
Zaditen is used to treat and prevent allergic diseases such as allergic rhinitis, urticaria, allergic dermatitis, hay fever, allergic bronchitis, atopic bronchial asthma.
Zaditen drops are used in the treatment and prevention of allergic conjunctivitis.
Zaditen is not recommended to take in such conditions:
- Lactation period;
- Increased individual sensitivity to the components of the drug.
With caution, the drug should be taken by patients suffering from liver failure and epilepsy.
Dosing and Administration
Tablets and syrup for children Zaditen taken orally during meals.
Adults pills appoint 1 pc. (1 mg) in the morning and in the evening. If the patient has a tendency to develop a sedative effect, it is recommended to slowly increase the dosage during the first week of therapy, starting with ½ tablet 2 times a day and bringing to a full dose. If necessary, the daily dose is increased to 4 tablets, that is, 2 tablets in the morning and evening. When using higher dosage effect occurs much faster.
Children are prescribed pills starting at the age of 3 years. The recommended dose is 1 tablet in the morning and evening.
For children under 3 years old, Zaditen is used in the form of a syrup. Its dosage depends on the age of the child:
- Up to 6 months - 0.05 mg / kg twice a day;
- 6 months - 3 years - 0.5 mg twice a day;
- After 3 years, 1 mg twice a day.
The duration of the course of therapy is at least 3 months. If you need to cancel Zadetena, do it gradually. During this period, possible relapses of disease.
Drops Zaditen prescribed for adults and children over 12 years. Recommended dosage: 1 drop in each eye in the morning and in the evening. Duration of application should not be more than 6 weeks.
At the beginning of treatment with the drug Zaditen, the development of such side effects as slight dizziness, increased drowsiness, slowing down of mental reactions is possible. Usually in a few days these manifestations disappear.
Also possible side effects include: increased appetite, sometimes dry mouth and dyspeptic symptoms; weight gain, cystitis, dysuria, thrombocytopenia.
The use of Zaditen drops can lead to the development of the following side effects:
- On the part of the visual system: dry eyes, reduced visual acuity, sometimes - photophobia, feeling of pain in the eyes, conjunctivitis, subconjunctival hemorrhage, with burrowing, a feeling of pain;
- Allergic reactions: sometimes - skin rashes, in some cases - eczema;
- Other symptoms: sometimes - fatigue, headache, in some cases - dryness in the mouth.
The therapeutic effect of Zaditen develops gradually, over a period of 1-2 months.
In the initial period of long-term therapy, Zaditen cannot immediately stop taking anti-asthmatic symptomatic and prophylactic drugs that the patient is taking. This is especially true for systemic glucocorticoids.
With simultaneous use of Zadyten and bronchodilators, it is sometimes necessary to reduce the dosage of the latter.
In patients who take antidiabetic agents, when prescribing Zaditen, it is necessary to control the level of platelets in the peripheral blood.
When prescribing this drug in patients with a history of epilepsy, caution should be exercised, since Zaditen may reduce the threshold of convulsive readiness.
Zaditen able to enhance the effectiveness of drugs, overwhelmingly acting on the central nervous system, as well as antihistamines and alcohol.
Droplets contain preservative benzalkonium chloride, which can penetrate the material of soft contact lenses. To prevent such exposure, it is recommended to remove contact lenses before the introduction of the drug and wear them after at least 15 minutes have passed after instillation.
In the case of the use of drops Zadyten simultaneously with other eye drops, it is important to take a break between their instillations for at least 5 minutes.
Do not use drops Zadeten with irritation or inflammation of the eyes.
When you receive Zaditen you need to avoid potentially dangerous activities that are associated with the need for quick psychomotor reactions and increased attention. Driving is also included in this category of activity.
Analogues of tablets Zaditen are Ketotifen tablets. By analogy drops Zaditen include drops Daltifen.
Terms and conditions of storage
Zaditen needs to be stored in the place unavailable to children, at a temperature up to 25ºС. The shelf life of the tablets - 4 years, syrup for children and eye drops - 2 years.
Zaditen eye drops should be used within one month after opening the bottle. It is prohibited to use them longer than this period.