Voltaren is a non-steroidal anti-inflammatory drug, cyclooxygenase inhibitor, which has analgesic, anti-inflammatory and antipyretic effects.
Release form and composition
Make several dosage forms of Voltaren:
- Solution for injection for intramuscular injection containing 25 mg of diclofenac sodium in 1 ml. In 3 ml ampoules, 5 ampoules per pack;
- Coated tablets containing 25 or 50 mg of diclofenac sodium in 1 tablet. 10 tablets in blisters;
- Retard tablets, coated, containing 100 mg of diclofenac sodium in 1 tablet, 10 pieces in a blister;
- Rectal suppositories containing 25, 50 or 100 mg of diclofenac sodium in 1 candle. 5 pieces in blisters.
Indications for use
According to the instructions, Voltaren is indicated for use in the following cases:
- Rheumatoid arthritis, including juvenile (Voltaren tablets are used exclusively in 25 mg tablets or rectal suppositories 25 mg);
- Ankylosing spondylitis;
- Pain in the spine;
- Rheumatic diseases of extra-articular soft tissue;
- Post-traumatic pain, swelling and inflammation of the soft tissues due to injuries;
- Gynecological diseases, including primary dysmenorrhea, accompanied by severe pain;
- Migraine attacks (only rectal Voltaren suppositories are used);
- Gout (only Voltaren tablets are used).
According to the instructions, Voltaren is contraindicated in the following cases:
- Hypersensitivity to diclofenac sodium or auxiliary components of the drug, analgin intolerance;
- Gastric or duodenal ulcer, Crohn's disease, colitis, gastritis;
- Children's age up to 6 years (for all dosage forms);
- Children's age up to 14 years (for Voltaren Retard tablets);
- Disorders in the work of the blood system of unexplained nature;
- Pregnancy 3 trimester;
- Severe disorders of the cardiovascular system, kidneys and liver;
- Hemorrhoids, proctitis, bleeding from the rectum (for rectal suppositories).
With caution Voltaren prescribed to patients:
- Old age with underweight;
- Which in the past had gastric and duodenal ulcers;
- With impaired hemostasis;
- With gastrointestinal bleeding in history.
Dosing and Administration
Voltaren tablets are taken regardless of the meal, swallowing whole and squeezing half a glass of water. Before taking it is not recommended to divide or crush the pill. The initial dose of Voltaren is 150 mg per day, divided into several doses. If a patient is prescribed long-term treatment, as a rule, Voltaren is sufficient in a dose of 75-100 mg per day.
For children aged 6–15 years, Voltaren is prescribed exclusively in tablet form at a dose of 0.5–2 mg per kg of body weight, divided into several doses.
Retard tablets prescribed in a dose of 100 mg once a day, preferably in the evening.
Voltaren in the form of a solution for injection is intended for intramuscular injection. It is not recommended to do injections more than 2 days in a row. If necessary, the solution is combined with other dosage forms of Voltaren, while ensuring that the total daily dose of the drug does not exceed 150 mg.
As a rule, Voltaren solution is prescribed in a dose of 75 mg (1 ampoule) per day. In the case of pronounced pain syndrome, the dose may be increased to 150 mg (2 ampoules) per day with an interval of several hours. In this case, the second injection should be done in the opposite buttock.
Rectal suppositories Voltaren prescribed in a dose of 100-150 mg, divided into 2-3 doses. As a rule, suppositories are prescribed for the night. If voltaren therapy with candles is combined with the use of other dosage forms of the drug, it is necessary to ensure that the daily dose of diclofenac sodium does not exceed 150 mg.
The use of Voltaren can cause the following side effects:
- Gastrointestinal tract: nausea and vomiting, stomach pain, flatulence, abnormal stool, ulcerative lesions of the stomach and duodenum 12, gastrointestinal bleeding;
- Cardiovascular system: tachycardia, hypertension, chest pain;
- Central and peripheral nervous systems: disorientation, dizziness, paresthesia, headache, disturbed sleep and wakefulness, mood swings, irritability, fatigue, impaired memory, trembling of limbs, nightmares, depression, anxiety;
- Skin: skin rash, urticaria, erythema multiforme, alopecia, eczema, Stevens-Johnson syndrome, phytosensitization, Lyell's syndrome, erythroderma;
- Sense organs: tinnitus, impaired hearing and vision, changes in taste;
- Hematopoietic organs: leukopenia, agranulocytosis, anemia, thrombocytopenia;
- Urogenital system: hematuria, edema, nephrotic syndrome, interstitial nephritis.
With long-term use of Voltaren patients should monitor the picture of peripheral blood, kidney function and liver.
Since diclofenac sodium does not accumulate in the body, the development of chronic overdose is unlikely. In acute overdose, symptoms such as cramps, epigastric pain, nausea and vomiting, and coma occur.
Treatment: gastric lavage, taking activated charcoal, conducting symptomatic therapy, receiving alkalizing agents. In some cases, the use of glucocorticosteroids.
The use of Voltaren does not affect the control of potentially dangerous mechanisms that require increased concentration of attention.
Structural analogues of Voltaren are:
Terms and conditions of storage
According to the instructions, Voltaren is recommended to be stored in a cool, dry and out of reach of children. The shelf life of all dosage forms of the drug is 2 years.