Nikoshpan - a drug with a vasodilating effect.
Release form and composition
Nikoshpan is available in the form of pale yellow tablets (50 each in polypropylene bottles screwed with plastic caps).
Active ingredients contained in 1 tablet:
- Drotaverine hydrochloride - 78 mg;
- Nicotinic acid - 22 mg.
Additional components of the tablets: lactose, talc, magnesium stearate, polyvidone and starch.
Indications for use
- Obliterating endarteritis;
- Cerebral angiospasm;
- Atherosclerosis of the coronary arteries;
- Angiospastic manifestations accompanying hypertensive and atherosclerotic encephalopathy;
- Angiospasms due to menopause;
- Hypersensitivity to the drug;
- Severe heart, kidney, liver failure.
During animal experiments and retrospective clinical trials of pregnant women, no teratogenic or embryotoxic effect of the drug was detected. However, experimental data are not enough to assess the degree of safety of Nikoshpan when it is used during lactation, therefore, during this period, the drug can be prescribed only after evaluating the safety-risk ratio.
Dosing and Administration
Nikoshpan taken orally, with migraine and angiospasm on an empty stomach, in other cases - after eating.
The daily dose is 1-3 tablets.
- Relatively often: headache, dizziness, skin rash, itching, fever, acidity, nausea, dyspepsia;
- In rare cases: insomnia, fainting, rapid heartbeat, hypotension, loss of consciousness, constipation.
Due to the lactose content, Nikoshpan can cause gastrointestinal disorders in patients suffering from lactose intolerance.
Nikoshpan reduces the effectiveness of oral contraceptives and hypoglycemic agents, as well as antiparkinsonic action of levodopa.
In the case of simultaneous use of statins increases the risk of myopathy and acute necrosis of skeletal muscles.
Terms and conditions of storage
Store at a temperature of 15-25 ° C out of the reach of children.
Shelf life - 5 years.