Sodium chloride is a drug used for rehydration and detoxification.
Release form and composition
Dosage form - solution for infusions of 0.9%: colorless, transparent (50, 100, 250, 500 and 1000 ml in Viaflo containers, in a carton 50 containers of 50 or 100 ml, 30 pcs. In 250 ml, 20 pieces - 50 ml, 10 pieces - 1000 ml, 200 and 400 ml in bottles, in a carton pack 1 bottle, in a cardboard box 24 (200 ml) or 12 (400 ml) packs.
Active ingredient - sodium chloride: in 1 ml - 9 mg.
The excipient is water for injection.
Indications for use
- Hyponatremia and hypochloraemia with dehydration;
- Isotonic extracellular dehydration;
- Intestinal obstruction;
- Large losses of extracellular fluid or insufficient intake of it (uncontrollable vomiting, diarrhea, cholera, toxic dyspepsia, extensive burns with severe exudation, etc.);
- Washing of wounds, mucous membranes of the nose and eyes.
In addition, sodium chloride is used to moisten the dressing material, dissolve and dilute drugs administered parenterally.
- Intracellular dehydration;
- Extracellular overhydration;
- Pulmonary edema;
- Swelling of the brain;
- Circulatory disorders threatening swelling of the brain and lungs;
- Acute left ventricular failure;
- The simultaneous use of large doses of glucocorticosteroids.
Relative (care should be taken because of the risk of complications):
- Arterial hypertension;
- Heart failure;
- Peripheral edema;
- Renal failure;
- Aldosteronism and other conditions accompanied by sodium retention in the body.
Dosing and Administration
Sodium chloride is used intravenously and externally.
Immediately before the introduction of the solution is heated to a temperature of 36-38 ˚C.
The doctor determines the dose, depending on the amount of loss of body fluids, chlorine and sodium. The average daily dose is 1000 ml. With severe intoxication and large losses may increase the dose to 3000 ml per day.
The average injection rate is 540 ml / hour.
Children with dehydration, which is expressed by a decrease in blood pressure, are prescribed 20-30 ml per kilogram of body weight. In the future, depending on laboratory parameters, the dosage regimen is adjusted.
Sodium chloride is used externally to wash wounds, nasal mucosa, eyes, and also to moisten the dressing material.
When using the solution as a base solvent (for dilution and dissolution of drugs administered parenterally), the recommended dose of Sodium Chloride is 50-250 ml per dose administered. The rate of administration and dose of the administered solution are determined by recommendations for the use of the main medicinal product.
With proper use of sodium chloride, the likelihood of side effects is minimal. In some cases, overhydration, acidosis, hypokalemia.
When using the drug as a solvent, the side effects are determined by the properties of soluble drugs.
You can only use a clear solution of sodium chloride, without visible inclusions, from intact packaging. It is necessary to enter immediately after connecting to the infusion system. It is forbidden to use a serial connection of plastic containers, since this is fraught with the development of an air embolism due to the suction of the remaining air in the first container.
In order to prevent air from entering the infusion system, it should be filled with a solution, completely releasing residual air from the container.
To enter the solution should be only using sterile equipment and compliance with all rules of asepsis and antisepsis.
You can add other drugs to the solution before or during the infusion of sodium chloride by injection into a specially designed area of the container.
When using sodium chloride as a solvent, it is necessary to determine the isotonicity of the resulting solution before the infusion. To enter the obtained solution should be immediately after preparation, storage is not allowed.
During the infusion, it is necessary to monitor the patient's condition, his biological and clinical indicators. It is important to evaluate the content of electrolytes in plasma and urine, especially with prolonged administration of large doses of isotonic solution.
Because of the immaturity of the kidney function in children, sodium excretion can be slowed down. For this reason, repeated infusions in children can be carried out only after determining the concentration of sodium in the blood.
Cases of the interaction of sodium chloride with other drugs are not described.
When mixing the solution with other drugs, it is necessary to visually monitor their compatibility: monitor the resulting solution for precipitation, color change, the appearance of insoluble complexes and crystals.
Terms and conditions of storage
Store at temperatures up to 25 C out of the reach of children. Freezing is allowed during transport.
- 200 and 400 ml - 1 year;
- 50 ml - 1.5 years;
- 100 ml - 2 years;
- 250, 500 and 1000 ml - 3 years.