Naxojin

Naxojin - antiprotozoal.

Release form and composition

Dosage form - tablets (6 pieces in dark glass bottles, in a cardboard bundle 1 bottle).

Active ingredient - nimorazole: in 1 tablet - 500 mg.

Excipients: microcrystalline cellulose, corn starch, stearic acid.

Indications for use

• Infectious diseases caused by Trichomonas vaginalis;
• Vaginitis caused by Gardnerella vaginalis;
• Amebiasis;
• Vincent's gingivitis (necrotizing ulceration);
• Giardiasis.

Contraindications

• Active neurological diseases;
• Disorders of the central nervous system;
• Pregnancy;
• Hypersensitivity to the drug.

Dosing and Administration

Naxojin should be taken orally, after meals.

Recommended doses for adults and children, depending on the indications:

• Trichomoniasis: adults - 250 mg twice a day for 6 days or 3 doses with 12-hour intervals of 1000 g (for example, the first dose in the morning, the second in the evening, the third - the next morning) or 2000 mg once; children - 15 mg / kg / day in 3 doses for 5-7 days;
• Infections caused by Gardnerella vaginalis: adults - 2000 mg once or 500 mg 2 times a day for 7 days;
• Giardiasis: adults - 500 mg twice a day; children - 15 mg / kg / day in 2 divided doses. The duration of therapy is 5-7 days;
• Amebiasis: adults - 500 mg 2 times a day; children - 20 mg / kg / day in 2 divided doses. The course of treatment is 5-10 days;
• Acute gingivitis Vincet: adults - 500 mg twice a day for 2 days.

Side effects

Dizziness, heartburn, nausea, drowsiness, skin rash.

special instructions

During treatment, it is forbidden to drink alcohol.

For infections of the genital organs, both sex partners must be treated at the same time, even if one of them has no symptoms.

Drug interaction

Possible interaction reactions in the case of simultaneous use of Naxogin with other drugs:

• Warfarin: increased anticoagulant effect;
• Phenytoin, lithium preparations: a decrease in their clearance;
• Phenobarbital: a decrease in the concentration of nimrazole in the blood plasma;
• Cimetidine: increase the concentration of nimrazole in the blood.

When alcohol is consumed during the administration of Naxogin, the likelihood of a disulfiram-like reaction is high.

Terms and conditions of storage

Store at a temperature not exceeding 30 ° C. Do not expose to light.

Shelf life - 5 years.