Mometasone is a synthetic glucocorticosteroid (GCS) for topical use with antiallergic, anti-exudative, antipruritic and anti-inflammatory action.
Release form and composition
Mometasone is available in the form of a cream of 0.1% and ointment of 0.1% (15 g in tubes).
The active ingredient of the drug is mometasone furoate: 1 g of cream and 1 g of ointment - 1 mg.
Auxiliary components of the cream: macrogol 20 cetostearyl ether, hexylene glycol, cetostearyl alcohol, glyceryl monostearate 40-55, titanium dioxide (E171), diluted phosphoric acid, aluminum starch octenyl succinate, white paraffin, white soft wax (wax, silica, aluminum wax, soft wax (white petroleum (white petroleum) (silica gel, white vaseline (vazelin, silica, silica, silica, white vaseline, silica, white paraffin, soft wax (white petroleum) (wax, silica, white vaseline), silica gel, silica, white vaseline, vaseline white, silica gel, white vaseline (silica, white vaseline, silica, silica, white vaselin, diluted with phosphoric acid), aluminum paraffin, white petroleum gel (white petroleum)), white paraffin, white wax (silica, white petroleum), diluted phosphoric acid), silica gel, one can use it, one can take it any
Auxiliary components of the ointment: hexylene glycol, white wax, diluted phosphoric acid, white soft paraffin (white petrolatum), propylene glycol monopalmitic stearate, purified water.
Indications for use
- Inflammation and pruritus in dermatoses, susceptible to the treatment of GCS;
- Conditions accompanied by symptoms of hyperkeratosis, including atopic and seborrheic dermatitis, psoriasis, chronic eczema.
- The period after a recent injury or surgery on the nose (use Mometasone is contraindicated until the wounds heal completely);
- Children's age up to 2 years;
- Hypersensitivity to the drug.
Dosing and Administration
Mometasone is applied externally. A thin layer of ointment or cream is applied to the affected skin once a day.
The required dosage form and duration of treatment are determined by the doctor for each patient individually.
Possible local side effects: itching and burning, skin atrophy, pink acne.
In rare cases, there are: acne-like rash, dryness and irritation of the skin, hypertrichosis, folliculitis, hypopigmentation, prickly heat, perioral dermatitis, allergic contact dermatitis, striae, secondary infections.
In the case of occlusive dressings, the risk of developing the described reactions increases.
In the case of systemic absorption, the drug can lead to reversible inhibition of the work of the hypothalamic-pituitary-adrenal system, the development of glucosuria, hyperglycemia, and Cushing syndrome.
After discontinuation of treatment, there is a chance of developing withdrawal syndrome.
Mometasone can be used during pregnancy and lactation if indicated.
The drug is not intended for use in ophthalmology. Do not let the cream / ointment in the eyes!
Patients who apply the drug to large areas of the skin or under the occlusive dressing should constantly monitor the function of the hypothalamic-pituitary-adrenal system in order to promptly diagnose the systemic effect of mometasone. For this purpose, determine the morning content of cortisol in the blood, conduct a test with stimulation of adrenocorticotropic hormone. If you establish a systemic effect, cancel the drug, or increase the intervals between the application of cream / ointment. Restoration of the functions of the hypothalamic-pituitary-adrenal system occurs soon after the cancellation of the GCS.
Mometasone is forbidden to be applied on the face, axillary areas and in the area of the inguinal folds.
Due to the high risk of systemic complications, cream / ointment is not recommended to be applied under waterproof underwear and occlusive dressings.
Treatment of children from 2 years should be under strict medical supervision. It should be borne in mind that in childhood there is a much higher risk of suppressing the work of the hypothalamic-pituitary-adrenal system (due to the large ratio of skin surface area and body weight relative to this value in adults), as well as the development of atrophic skin lesions and Cushing's disease .
Mometasone is contraindicated for the treatment of diaper dermatitis.
If after 2 weeks of treatment the improvement is not observed, you should consult a doctor to clarify the diagnosis.
In the case of the development of local infectious lesions during the period of drug treatment, it is necessary to prescribe an appropriate antifungal or antibacterial therapy. At the time of treatment of infectious complications the use of mometasone should be suspended.
Mometasone furoate incompatible chemical properties with alkalis. Information about other interaction reactions is missing.
Terms and conditions of storage
Store at a temperature up to 25 ºС in a dry, dark place, out of reach of children.
Shelf life - 3 years.