Miconazole - a drug used to treat fungal diseases.
Release form and composition
Miconazole is available in the following dosage forms:
- Tablets (in packs of 10 pcs.);
- Gel for oral administration (in tubes of 40 g);
- Liquid for external use (in aerosol containers of 30 g);
- Alcohol solution (in vials of 30 ml with a brush included);
- Solution for intravenous administration of 1% (in ampoules of 20 ml; 5 ampoules per pack).
The composition of 1 tablet contains the active substance: miconazole - 250 mg.
The composition of 1000 mg of gel for oral administration and liquid for external use, 1 ml of the solution for intravenous administration and alcohol solution includes the active substance: miconazole - 20 mg.
Indications for use
- Superficial and systemic mycoses, ringworms and onychomycosis caused by blastomycetes;
- Mycosis of the scalp;
- Blastomycetosis of the oral cavity, gastrointestinal tract, urinary organs;
- Fungal balanitis;
- Fungal infections with low immunological resistance of the body (for prevention).
- Congenital abnormal liver function (solution, pills and gel);
- Pregnancy (solution, tablets and gel);
- Hypersensitivity to the components of the drug.
Dosing and Administration
Tablets are taken orally. Miconazole dosage for the prevention and treatment of mycoses of the gastrointestinal tract for adults: 1 tablet 4 times a day, for children - 20 mg per 1 kg of body weight per day.
Miconazole gel is taken internally, holding in the mouth as long as possible. In case of mycoses of the oral cavity and the gastrointestinal tract, adults and older children are prescribed half a dosage spoon (2.5 ml) of the gel 4 times a day; young children - a quarter of the dosing spoon 4 times a day. Therapy should be continued for 7 days (minimum) after the disappearance of the symptoms of the disease.
A small amount of external liquid for skin diseases is applied to the affected areas and rubbed until completely absorbed. In most cases, after 2-6 weeks, the therapeutic effect occurs. Therapy should be continued for 7 days (minimum) after the disappearance of signs of the disease.
In the case of onychomycosis, the drug is applied to the affected nails, the surrounding skin, and covered with a bandage. Miconazole therapy is carried out until a new nail plate grows.
The drug in the form of an alcohol solution is applied to the affected nails with a brush 2 times a day.
The solution for intravenous administration is used for systemic mycoses at a dose determined on the basis of 10 mg per 1 kg of body weight per day. With good portability, it can be increased to 30 mg per 1 kg of body weight per day. The solution should be administered simultaneously, but not more than 600 mg in one administration, slowly over 30-60 minutes; drip is allowed in several doses. Immediately before use, miconazole is diluted with isotonic sodium chloride solution.
During the period of treatment with miconazole in the form of tablets and gel for oral use, nausea, diarrhea, allergic reactions may occur; in the form of an alcohol solution and liquid - allergic reactions, irritation; in the form of intravenous solution - skin rash, diarrhea, chills, thrombophlebitis, dizziness.
Before using miconazole, it is recommended to consult a doctor.
Miconazole with simultaneous use enhances the effect of difenina, oral hypoglycemic drugs, coumarin anticoagulants.
Terms and conditions of storage
Store in a dark place.