Mydocalm is a centrally acting muscle relaxant.
Release form and composition
Dosage form - coated tablets: round, convex on both sides, white or almost white, engraved on one side (“50” or “150”), with a faint characteristic odor (10 each in blisters, 3 each blisters in a carton box).
The composition of the drug:
- Active ingredient: tolperisone hydrochloride - 50 or 150 mg in 1 tablet;
- Auxiliary components: stearic acid, corn starch, microcrystalline cellulose, colloidal silicon dioxide, citric acid monohydrate, talc, lactose monohydrate.
Shell composition: titanium dioxide (E171), hypromellose, lactose monohydrate, colloidal silicon dioxide, macrogol 6000.
Indications for use
- Pathologically increased tone and spasms of striated muscles arising from organic diseases of the central nervous system: myelopathy, cerebral stroke, damage to the pyramidal tracts, encephalomyelitis, multiple sclerosis;
- Increased tone and muscle spasms, muscle contractures accompanying diseases of the organs of movement, including arthrosis of large joints, spondylosis, cervical and lumbar syndromes, spondylarthrosis;
- Little's disease (infantile cerebral spastic paralysis) and other encephalopathies that are accompanied by muscular dystonia;
- Diseases resulting from disorders of vascular innervation: intermittent angioedema, acrocyanosis (as part of combination therapy);
- Vascular obliterans: Raynaud’s disease, diabetic angiopathy, diffuse scleroderma, arteriosclerosis obliterans, thromboangiitis obliterans (as part of combination therapy).
Also Mydocalm is used for rehabilitation treatment in the period after trauma and orthopedic operations.
- Children's age up to 3 years;
- Myasthenia gravis;
- Hypersensitivity to the drug.
Dosing and Administration
Mydocalm should be taken orally, swallowing the pill whole, washed down with water, after a meal.
- Adults and children over 14 years: 50 mg 2-3 times a day with a gradual increase to 150 mg 2-3 times a day;
- Children 7-14 years: 2-4 mg / kg for 3 doses;
- Children 3-6 years: 5 mg / kg for 3 doses.
Possible side effects of Mydocalm:
- Central and peripheral nervous system: headache, muscle weakness;
- Cardiovascular system: arterial hypotension;
- Digestive system: a feeling of discomfort in the stomach, nausea and vomiting;
- Allergic reactions: rarely - urticaria, pruritus, erythema, anaphylactic shock, angioedema, bronchospasm.
The described reactions usually take place after reducing the dose of the drug.
In order to avoid complications, Mydocalm should be taken strictly in accordance with the recommendations of the attending physician.
Research on the effect of the drug on the reaction rate and ability to concentrate was not conducted. However, according to the long-term practice of using Mydocalm, there was no negative impact.
Tolperisone enhances the action of niflumic acid, which may require a reduction in its dose.
Clonidine, peripheral muscle relaxants, general anesthetics and psychotropic drugs enhance the effect of tolperisone.
Although Mydocalm has an effect on the central nervous system, it does not cause a sedative effect, so if necessary it can be combined with hypnotics, sedatives, and agents containing ethanol.
Terms and conditions of storage
Store at a temperature of 15-30 ° C in the reach of children, protected from moisture.
Shelf life - 3 years.