Libexin is an antitussive drug.
Release form and composition
Libeksin is produced in the form of tablets: flat, round, almost white or white in color, with a facet on both sides, with an engraving “LIBEXIN” on one side and the risks dividing the tablet into four parts, on the other (20 pieces in blisters, 1 blister in a carton box).
The composition of 1 tablet includes:
- Active ingredient: prenoxdiazine hydrochloride - 100 mg;
- Auxiliary components: glycerin (glycerol), talc, corn starch, magnesium stearate, povidone, lactose monohydrate.
Indications for use
- Night cough in patients with heart failure;
- Unproductive cough of any etiology (for pneumonia, influenza, catarrh of the upper respiratory tract, chronic and acute bronchitis, emphysema).
Libeksin is also used during the preparation of patients for bronchoscopic or bronchographic studies.
- Diseases associated with abundant bronchial secretion;
- Condition after inhalation anesthesia;
- Galactose intolerance, glucose-galactose malabsorption or lactase deficiency;
- Hypersensitivity to the drug.
Libexin should be used with caution in children.
Dosing and Administration
Libexin is taken orally without chewing (to avoid anesthesia of the oral mucosa).
The average adult single dose is 100 mg (1 tablet), the multiplicity of reception - 3-4 times a day. In more complex cases, it is possible to increase the daily dose to a maximum of –9 tablets (3 to 3 times a day, 2 tablets or 3 tablets 3 times a day).
Children Libexin prescribed on the basis of body weight and age. The average single dose is 25-50 mg (1 / 4-1 / 2 tablets) 3-4 times a day. The maximum daily dose for children - 2 tablets.
In preparing patients for bronchoscopy, Libex at a dose of 0.9-3.8 mg / kg of body weight is combined with atropine at a dose of 0.5-1 mg. Drugs should be applied 1 hour before the procedure.
During therapy, the following side effects may develop:
- Nervous system: with high doses of Libexin, fatigue, slight sedation;
- Gastrointestinal tract: rarely - dryness in the throat or mouth, anesthesia (loss of sensitivity and temporary numbness) of the oral mucosa; less than 10% of cases - a tendency to constipation, stomach pain, nausea;
- Allergic reactions: rarely - skin rash, angioedema.
As a rule, fatigue and sedation appear when taking the drug in doses exceeding the recommended. These symptoms stop spontaneously within a few hours after discontinuation of the drug.
Patients with lactose intolerance may receive complaints from the gastrointestinal tract during treatment, since each tablet contains 0.38 mg of lactose.
Taking high doses of Libexin may slow down the rate of reactions. In this case, the question of the possibility of driving vehicles or performing work associated with increased danger should be addressed individually.
It is not recommended to take Libexin with expectorant and mucolytic drugs at the same time, as it may make it difficult to separate the sputum diluted by the latter.
There are no preclinical or clinical data on the interaction of Libexin with other drugs.
Terms and conditions of storage
Keep out of reach of children at temperature up to 25 ° C.
Shelf life - 5 years.