Lactulose is a means of stimulating intestinal peristalsis, which has a laxative and hypoazotemic effect.
Release form and composition
Lactulose is available in the form of a syrup for oral administration: 200, 500 or 1000 ml in plastic bottles, in a cardboard bundle one bottle complete with a measuring cup.
The composition of the drug (in 1 ml):
- Active ingredient: lactulose - 667 ml;
- Auxiliary components: citric acid and purified water.
Indications for use
Lactulose is used to treat the following diseases:
- Constipation, incl. chronic;
- Intestinal dysbacteriosis;
- Enteritis caused by Shigella or Salmonella, as well as salmonello carrier;
- Hepatic encephalopathy, incl. precoma and coma (treatment and prevention);
- The syndrome of putrid dyspepsia in young children, which developed as a result of acute food poisoning.
Lactulose is also prescribed to soften the stool (relieve bowel movements), for example, in the postoperative period, with hemorrhoids, pain syndrome after removal of hemorrhoids, the need for anus and / or colon surgery, etc.
- Intestinal obstruction;
- Rectal bleeding (not caused by hemorrhoids);
- Suspected appendicitis;
- Kolo and ileostomy;
- Hypersensitivity to the drug.
Patients with diabetes mellitus should be under constant observation during the treatment period, especially if they have assigned Lactulose in connection with hepatic encephalopathy.
Dosing and Administration
Lactulose is intended for oral administration.
The dose in each case is determined individually.
In case of hepatic encephalopathy, adults are prescribed 45-90 ml of syrup per day in 2-3 doses, the maximum daily dose is 190 ml, and in case of other indications - 15-45 ml per day.
Daily doses for children: up to 1 year - 5 ml, older than 1 year - 5-15 ml.
In some cases during the treatment period, the following side effects may occur: abdominal pain, flatulence, diarrhea, loss of electrolytes.
Lactulose should not be taken with abdominal pain, nausea and vomiting.
In the case of diarrhea during the treatment period, the drug should be discontinued.
In case of gastrocardiac syndrome, it is recommended to gradually increase the dose in order to avoid flatulence. This phenomenon usually resolves spontaneously after 2-3 days after starting the drug.
With long-term treatment (over 6 months) in high doses, regular monitoring of the level of electrolytes in the blood serum is necessary.
Magnesium hydroxide, calcium carbonate and magnesium carbonate reduce the decrease in pH in the large intestine caused by lactulose, and prevent the development of its effect.
Neomycin reduces the effectiveness of lactulose.
Terms and conditions of storage
Keep out of the reach of children and protected from light at a temperature of 5 to 25 ºС.
Shelf life - 2 years.