Xymelin - a drug with a vasoconstrictor action for local use in ENT practice.
Release form and composition
Dosage Forms of Xymelin:
- Nasal drops of 0.05% and 0.1% (in plastic bottles, droppers with a volume of 10 ml, 1 bottle in carton packs);
- Spray nasal 0.05% and 0.1% (in dark glass vials, equipped with a spray, a volume of 10 or 15 ml, 1 bottle in carton packs).
The active ingredient of the drug is xylometazoline hydrochloride. Its content: in 1 ml of 0.05% drops and spray - 0.5 mg, in 1 ml of 0.1% drops and spray - 1 mg.
Excipients of drops and spray: sodium hydrophosphate dihydrate, sodium chloride, sodium dihydrophosphate dihydrate, benzalkonium chloride (in the form of a 10% solution of benzalkonium), disodium edetate, purified water.
Indications for use
- Acute allergic rhinitis;
- Acute respiratory diseases, accompanied by rhinitis;
- Preparation of patients for diagnostic manipulations in the nasal passages;
- Otitis media (in this case, the drug is used to reduce swelling of the mucous membrane of the nasopharynx).
- Atrophic rhinitis;
- Surgical procedures on the meninges in the history of the disease;
- Pronounced atherosclerosis;
- Arterial hypertension;
- Children under 2 years old - for the drug 0.05%, up to 6 years old - for the drug 0.1%;
- Hypersensitivity to the drug.
During lactation, Xymelin can be appointed only after a careful assessment of the ratio of the intended benefits to the mother and the possible risks to the infant.
Relative (special caution required):
- Angina III-IV functional class;
- Prostate hyperplasia;
Dosing and Administration
Both dosage forms of Xymelin are intended for intranasal administration.
Drops and spray 0.05% prescribed for children 2-6 years old - 1-2 drops or 1 injection in each nasal passage 1-2 times a day.
Drops and spray 0.1% prescribed for children over 6 years of age and adults - 2-3 drops or 1 injection in each nostril.
If necessary, instillation can be repeated.
You can use the drug no more than 3 times a day. The maximum duration of treatment is 7 days. If more prolonged use is required, consultation of the doctor is necessary.
Basically, the drug is well tolerated. With frequent and / or long-term use of Xymelin, the following undesirable reactions may occur: burning, dryness and / or irritation of the nasopharyngeal mucosa, hypersecretion, sneezing. Sometimes there is swelling of the mucous membrane.
In rare cases, systemic side effects of xylometazoline may develop: arrhythmias, tachycardia, increased blood pressure, palpitations, headache, blurred vision, insomnia, vomiting; with prolonged use in high doses - depression.
If the recommended doses are exceeded, there may be: a decrease in body temperature, bradycardia, an increase in blood pressure with a subsequent decrease, as well as an increase in the severity of side effects. Symptomatic overdose treatment.
When used in recommended doses, Xymelin does not adversely affect visual acuity, reaction rate and ability to concentrate.
Xymelin should not be used simultaneously with tricyclic antidepressants and monoamine oxidase inhibitors, since possible increase in blood pressure.
Terms and conditions of storage
Store at a temperature of 15-25 ºС out of the reach of children.
Shelf life - 2 years.