Xylen - alpha adrenomimetic; a vasoconstrictor intended for topical use in an ENT practice.
Release form and composition
Dosage Forms of Xylene:
- Nasal drops of 0.05% and 0.1% (10 ml each in polymeric or dark glass bottles with a dropper nozzle, 1 bottle each in carton packs);
- Spray nasal 0.05% and 0.1% (10 ml each in polymeric or dark glass bottles with a dropper head, 1 bottle each in carton packs).
The active ingredient of the drug is xylometazoline hydrochloride: in 1 ml of 0.05% drops and spray - 0.5 mg, in 1 ml of 0.1% drops and spray - 1 mg.
Indications for use
- Symptomatic treatment of sinusitis and acute rhinitis of various etiologies, incl. rhinitis in acute respiratory diseases and allergic rhinitis;
- Reducing swelling of the nasopharynx with otitis media;
- Preventive use in preparation for the diagnostic procedures in the nasopharynx, in particular, rhinoscopy.
- Atrophic rhinitis;
- Severe arterial hypertension;
- Severe atherosclerosis;
- Surgical procedures on the meninges in history;
- Children under 2 years old - for 0.05% spray, up to 6 years old - for 0.1% drops and spray;
- Lactation period (or should stop breastfeeding);
- Individual hypersensitivity to xylometazoline or auxiliary components of the drug.
Relative (special caution required):
- Coronary heart disease;
- Benign prostatic hyperplasia;
Dosing and Administration
Both dosage forms of xylene are intended for intranasal use. Before each injection, the nasal passages must be cleaned of mucus.
- Adults and children over 6 years old - 1-2 drops of 0.1% drops or 1 injection of 0.1% spray in each nasal passage 2-3 times a day;
- Children 2-6 years old - 1-2 drops of 0.05% drops or 1 injection of 0.05% spray in each nasal passage 1-2 times a day;
- Children from birth to 2 years - 1-2 drops of 0.05% drops in each nasal passage 1-2 times a day.
The minimum interval between applications is 8 hours.
The duration of treatment is determined by the attending physician, but it should not exceed 5 days.
If the patient missed the time of drug administration, it is not possible to double the dose in the next procedure.
Basically, Xylen is well tolerated. Adverse reactions are usually noted with frequent use of the drug or the introduction of high doses.
Possible side effects: dryness and irritation of the mucous membrane of the nasopharynx, sneezing, hypersecretion, paresthesia, tachycardia, feeling of heartbeat, arterial hypertension; in rare cases - swelling of the nasal mucosa, headaches, insomnia, reduced visual acuity, arrhythmias, depressive states.
With long-term treatment (more than 5 days), nasal mucous edema and atrophic rhinitis may develop.
When excessive doses are used, there is a chance of developing systemic side effects characteristic of xylometazoline, such as paresthesias, blood pressure lability, tachycardia, convulsions. There is no specific antidote. In case of overdose, you should cancel Xilen, conduct symptomatic therapy and measures aimed at maintaining the function of the cardiovascular system.
Xylene is not intended for the treatment of chronic rhinitis.
During pregnancy, xylometazoline is prescribed only in extreme cases. In this case, it should be used in minimum doses of no more than 3 days in a row.
After each instillation, it is necessary to clean the dropper and close the bottle tightly with a cap.
During treatment, it is recommended to refrain from performing activities that require speed of reactions and increased concentration of attention.
Patients receiving monoamine oxidase inhibitors can use Xylometazoline no earlier than 2 weeks after their cancellation.
Xylene should not be used during treatment with tricyclic antidepressants.
Terms and conditions of storage
Store in original packaging at a temperature between 15 and 25 ºС.
Shelf life - 3 years.