Isofra is an antibiotic drug of the aminoglycoside group used in combination therapy for infectious and inflammatory diseases of the upper respiratory tract.
Release form and composition
Izofru produced in the form of 1.25% nasal spray, 15 ml in plastic bottles complete with a sprayer, 1 bottle in carton packs.
The composition of 1 ml spray includes 12.5 mg (8 thousand IU) of framycetin sulfate.
Excipients: sodium chloride, methyl parahydroxybenzoate, distilled water, citric acid.
Indications for use
Izofru is used as part of a combination treatment for infectious and inflammatory diseases of the upper respiratory tract:
- Sinusitis (in cases of no damage to the septum).
Also, the drug is prescribed for the prevention and treatment of inflammatory processes after surgery.
Isofra is contraindicated in case of hypersensitivity to framycetin, auxiliary components, as well as to other antibiotic preparations from the group of aminoglycosides.
Strictly controlled and adequate clinical studies of the safety of Isofra use by lactating and pregnant women have not been conducted.
Dosing and Administration
A single dosage of the drug - 1 injection into each nostril. The range of application of Isofra:
- Adults - 4-6 times a day;
- Children - 3 times a day.
The average duration of the treatment course is 7 days.
When applying the bottle with the tool must be kept in an upright position.
Isofra in rare cases can cause allergic reactions in the form of skin manifestations.
If the effect is absent or weakly pronounced during the course of treatment, Isofra should be withdrawn. It should be borne in mind that longer use of the drug can lead to disruption of the natural microflora of the nasopharynx (dysbiosis).
Isofra is not recommended for washing the paranasal sinuses.
Analogues of Isofra on the mechanism of action are: Amikozit, Nebtsin, Netromitsin, Garamycin, Nettacin, Selemycin, Tobramycin, Tobropt, Fartsiklin, Hemacin and other aminoglycosides.
Terms and conditions of storage
Keep out of reach of children at temperature up to 25 ° C.
The shelf life of the drug - 3 years.