Ibuprofen is a non-steroidal anti-inflammatory drug.
Release form and composition
The drug Ibuprofen is available in the form of tablets, suspensions, gel, ointment, suppositories (suppositories).
Ibuprofen tablets are coated pink, round-shaped, biconvex. They are placed in 10 pieces. in cell blister packs, then 2 or 5 packs in carton packs.
Ibuprofen suspension is sold in glass bottles of 100 g, which together with a measuring spoon are packed in cardboard boxes.
Gel 5% Ibuprofen for external use is available in aluminum tubes of 20 g, 30 g, 50 g and 100 g, which are placed in the package.
Ointment for external use Ibuprofen 5% is sold in aluminum tubes of 25 g, which are placed in packs of cardboard.
Rectal suppositories for children Ibuprofen are available in 5 pcs. in blisters, with a cardboard box containing 2 such packages.
The active ingredient of the drug Ibuprofen is ibuprofen, which has anti-inflammatory, analgesic and moderate antipyretic effect.
Ibuprofen tablets contain ibuprofen (200 mg) and excipients: potato starch, colloidal silicon dioxide, magnesium stearate, beeswax, vanillin, edible gelatin, wheat flour, magnesium hydroxycarbonate, low molecular weight povidone, titanium dioxide, azorubin dye, sucrose.
Ibuprofen suspension contains ibuprofen (100 mg) and excipients: carboxylated methyl cellulose sodium, cremophore RH-40, magnesium aluminum silicate, propylene glycol, glycerin, sucrose, propyl hydroxybenzoate, methyl hydroxybenzoate, sodium hydrogen phosphate, propidhydroxybenzoate, methyl hydroxybenzoate, sodium hydrogen phosphate, citrate, citric cream, citrate, citric acid, glycerol, sucrose, propylhydroxybenzoate, methyl hydroxybenzoate. , dye orange yellow, purified water.
Gel 5% Ibuprofen is composed of ibuprofen (50 mg) and excipients: carbomer 940, ethanol, propylene glycol, methyl para-hydroxybenzoate, triethanolamine, dimexide, lavender oil, non-rolybic oil, purified water.
The composition of the ointment 5% Ibuprofen includes ibuprofen (5 g) and excipients: macrogol 1500, dimexide, macrogol 400.
Rectal suppositories Ibuprofen contain ibuprofen (60 mg) and solid fat.
Indications for use
Ibuprofen tablets are used in adults and children after 6 years with the following pathologies:
- Inflammatory processes of the spine and joints (gouty arthritis, osteoarthrosis, ankylosing spondylitis, rheumatoid arthritis);
- Mild pain of various origins (headache, toothache, migraine, myalgia, neuralgia, primary algomenorrhea, post-traumatic pain, postoperative pain);
- Febrile syndrome in infectious and colds.
Ibuprofen tablets are designed for symptomatic therapy and do not affect the progression of the disease.
Ibuprofen suspension is used in infants and young children, as well as in adults with such diseases and conditions:
- Weak and moderate pain syndrome, including toothache, painful teething, headache, migraine, muscle and joint pain, ear pain;
- Increased body temperature for colds, acute respiratory viral infections, influenza, pharyngitis, childhood infections, after vaccination;
- Algomenorrhea, adnexitis;
- Traumatic inflammation of soft tissues.
Gel 5% and maz 5% Ibuprofen is prescribed in the treatment of the following pathologies:
- Degenerative and inflammatory diseases of the musculoskeletal system;
- Aggravation of gout;
- Pain with rheumatism;
- Shoulder girdle periarthritis;
- Deforming osteoarthritis;
- Ankylosing spondylitis;
- Osteochondrosis with radicular syndrome;
- Myalgia, lumbago, bursitis, tendovaginitis, tendonitis, injuries without compromising the integrity of soft tissues.
Ibuprofen suppositories are used in children aged 3 months - 2 years in such conditions:
- Mild or weak pain syndrome (toothache, headache and ear pain, pain when ligament damage occurs);
- Fever with acute respiratory infections, influenza, infectious diseases, in the post-vaccination period.
Ibuprofen tablets are contraindicated in the case of the following diseases and conditions:
- Erosive and ulcerative lesions of the digestive system in exacerbations (ulcerative colitis, Crohn's disease, ulcerative lesions of the stomach and duodenum);
- Inflammatory processes in the intestine;
- Intracranial hemorrhage;
- Gastric bleeding;
- Hypocoagulation, hemophilia, hemorrhagic diathesis;
- Severe liver disease, including severe liver failure;
- Severe kidney disease;
- Increased individual sensitivity to the components of the drug.
Ibuprofen tablets are not recommended for children under 6 years of age.
With caution, the drug is prescribed to patients who suffer from such pathologies:
- Coronary heart disease, arterial hypertension, heart failure;
- Peripheral arterial diseases, cerebrovascular pathologies;
- Diabetes, dyslipidemia;
- Colitis, enteritis, gastritis.
Ointment and gel Ibuprofen is not used in the case of such diseases and conditions:
- Violation of the integrity of the skin;
- Eczema, weeping dermatosis;
- Hematopoiesis disorders;
- Aspirin Triad;
- Hypersensitivity to the components of the drug.
There are the following contraindications to the use of Ibuprofen suppositories:
- Ulcerative lesions of the gastrointestinal tract, gastrointestinal bleeding;
- Inflammatory bowel disease;
- Hemophilia, leukopenia, hypocoagulation;
- Hepatic or renal failure;
- Hearing loss;
- Hypersensitivity to drug components or acetylsalicylic acid.
Ibuprofen candles are taken with caution if the child suffers from ulcerative colitis, gastritis, urticaria, bronchial asthma. Care must be taken when prescribing this agent while taking indirect anticoagulants, diuretics, antiplatelet agents, glucocorticosteroids, blood pressure lowering drugs.
Dosing and Administration
Ibuprofen tablets prescribed:
- Rheumatoid arthritis - 800 mg 3 times a day;
- Ankylosing spondylitis and osteoarthritis - 400-600 mg 3-4 times a day;
- Moderate pain syndrome - 400 mg 3 times a day;
- Sprains and injuries of soft tissues - 600 mg 2-3 times a day.
The daily dose of the drug should not exceed 2.4 g.
Suspension Ibuprfen is prescribed for children at the rate of 20-40 mg / kg per day, divided into several doses. For adults use 200-800 mg of the drug 2-3 times a day.
Ibuprofen gel and ointment is applied to the affected place with a strip of 5-10 cm and carefully rubbed into the skin. Repeat 3-4 times a day, the course of therapy - 2-3 weeks.
Rectal suppositories Ibuprofen is used in a dosage of 5-10 mg / kg of body weight of the child, no more than 3-4 times a day. In this case, children 3-9 months prescribed for 1 candle (60 mg) three times a day, but not more than 180 mg / day. Children aged 9-24 months - 1 candle 4 times a knock, but not more than 240 mg / day. When fever suppositories Ibuprofen are used for no more than 3 days, with pain syndrome - no more than 5 days.
Possible side effects of Ibuprofen include:
- Nausea, vomiting, constipation, flatulence, diarrhea, loss of appetite;
- Bronchospasm, shortness of breath;
- Swelling of the eyelids and conjunctiva, irritation and dryness of the eyes, double vision or blurred vision, noise or tinnitus, hearing impairment;
- Nervousness, anxiety, insomnia, dizziness, headache, depression, drowsiness, psychomotor agitation;
- Increased blood pressure, tachycardia, heart failure;
- Leukopenia, agranulocytosis, thrombocytopenic purpura, thrombocytopenia, anemia;
- Pruritus, skin rash, angioedema, anaphylactic shock, allergic rhinitis, erythema multiforme;
- Increased sweating.
Ibuprofen tablets are not recommended to be taken during pregnancy and breastfeeding. Ibuprofen suspension, ointment and gel can be taken with caution only in the second and third trimesters of pregnancy.
The analogues of Ibuprofen include: Ibuprof, Ibupron, Dolgit, Burana, Brufen, Bren, Nurofen, Bonifen, Advil, Reumafen, Profen, Ipren, Ibusan.
Terms and conditions of storage
Ibuprofen should be stored in places inaccessible to sunlight at temperatures up to 25 ºС. Shelf life - 2 years.