Guttalax is a laxative medication that stimulates intestinal motility.
Release form and composition
Release Guttalaks drops in dropper bottles of 15 or 30 ml. 1 ml of the drug (or 15 drops) contains the active ingredient - sodium picosulfate - in the amount of 7.5 mg. Auxiliary components are: purified water, sorbitol 70%, sodium methyl parahydroxybenzoate, hydrochloric acid.
Indications for use
According to the instructions, Guttalaks is indicated for use as a laxative agent in the following cases:
- Constipation caused by hypotension or atony of the large intestine (in bedridden patients, due to old age, in the postpartum and postoperative periods, during breastfeeding);
- Constipation caused by therapy with certain medications;
- Regulation of the chair with proctitis, hemorrhoids, anal fissures (in order to soften the consistency of feces);
- Irritable bowel syndrome, causing constipation, gallbladder disease;
- Constipation resulting from a violation of the diet or dysbiosis.
According to the instructions Guttalaks should not be used in the following cases:
- Children's age up to 4 years;
- Intestinal obstruction;
- First trimester of pregnancy;
- Severe pain in the abdomen, accompanied by nausea, vomiting (this can be a symptom of severe conditions and requires immediate medical attention);
- Obstructive bowel disease;
- Severe dehydration;
- Hypersensitivity to the active or auxiliary components of the drug;
- Acute inflammatory bowel disease;
- Hereditary intolerance to fructose.
Dosing and Administration
Guttalaks take inside. Children aged 4-10 years, the drug is prescribed in a dose of 5-10 drops per day (2.5-5 mg), older than ten years and adults - 10-20 drops per day (5-10 mg).
To get a laxative effect of Guttalax in the morning, you should take it the day before going to bed.
The use of Guttalax can cause the following side effects from various systems of vital activity of the organism:
- Digestive system: nausea, vomiting, discomfort and abdominal pain, diarrhea;
- Nervous system: dizziness and subsequent syncope caused by vasovagal reaction (for example, stress during defecation, abdominal cramps);
- Allergic reactions caused by hypersensitivity to the components of the drug, including skin rashes and angioedema.
In the case of excessive doses of Guttalax, dehydration, diarrhea, impaired water and electrolyte balance, reduction of blood pressure, convulsions, hypokalemia can occur. In addition, there have been feedback from patients about possible ischemia of the muscles of the large intestine due to the administration of high doses of medication, far exceeding those recommended for the treatment of constipation.
Like other laxative drugs, Guttalaks in case of chronic overdose causes chronic diarrhea, hypokalemia, severe abdominal pain, urolithiasis, secondary hyperaldosteronism. With continued abuse of the drug, development of damage to the renal tubules, muscular weakness and metabolic alkalosis caused by hypokalemia are likely.
If a patient has the above symptoms of an overdose, it is recommended to induce vomiting in order to reduce the absorbability of the drug, to do a gastric lavage. In case of dehydration, the fluid should be replenished, the electrolyte balance should be adjusted, and antispasmodic medication should be prescribed.
The simultaneous use of Guttalax in excessive doses and glucocorticosteroids or diuretics is not recommended, since it increases the likelihood of electrolyte disturbances. In turn, electrolyte imbalance increases the body's sensitivity to cardiac glycosides.
In the case of simultaneous prescription of antibiotics, the laxative effect of Guttalax is reduced.
It is allowed to use Guttalaks during pregnancy (2 and 3 trimesters) and breastfeeding, as long-term experience with the application did not reveal its negative impact on the fetus or child. In the course of preclinical studies, no teratogenic effect on reproductive function was observed.
Guttalax therapy is not recommended for more than 10 days in a row, as its long-term use may cause electrolyte imbalance, hypokalemia, and dehydration.
Patients need to take into account that 1 ml of drops contains sorbitol in the amount of 450 mg. Guttalaks has no taste, so children can add it to food.
Since Guttalax can cause vasovagal reactions (i.e., intestinal spasms) causing dizziness and even fainting, it is recommended to manage with caution potentially dangerous mechanisms that require increased concentration.
Structural analogues of Guttalaks and drugs with a similar mechanism of action are:
- Sodium picosulfate;
Terms and conditions of storage
According to the instructions, Guttalaks stored at a temperature not exceeding 25 degrees Celsius. Expiration date - 3 years from the moment of release.