Glutamic acid

Glutamic acid is a nootropic drug that improves metabolism in the brain. It is a replaceable amino acid that acts as a mediator with high metabolic activity in the brain and stimulates the course of redox processes in it.

Release form and composition

Dosage form of the drug - enteric-coated tablets.

Each tablet contains:

• 250 mg of L-glutamic acid as an active substance;
• Auxiliary components: povidone, calcium stearate, stearic acid, potato starch;
• Shell: sugar, magnesium carbonate light, povidone, colloidal silicon dioxide, talc, titanium dioxide, yellow wax, light mineral oil, patented blue V dye (E131).

Glutamic acid tablets are sold in 10 pcs. in blister strip packaging.

Indications for use

According to the instructions for Glutamic acid, under its influence stimulation is stimulated at the synapses of the central nervous system, ammonia is neutralized and excreted from the body, the body’s resistance to oxygen starvation is increased, and glycolysis (splitting) in the tissues and blood is normalized. In addition, the tool has the properties of the hepatoprotector and the ability to suppress the secretory function of the stomach.

Considering the described characteristics of the active substance, the use of Glutamic acid is advisable as one of the components of complex therapy:

• Epilepsy (mainly in patients suffering from minor seizures with epileptic mental equivalents);
• Psychoses (involutional, somatogenic, intoxication);
• Schizophrenia;
• Psychogenic (reactive) depression;
• Mental exhaustion;
• Progressive myopathy;
• Delays in mental development of a different nature of origin;
• Insomnia;
• Cerebral palsy;
• Toxic neuropathy associated with the use of isonicotinic (g-pyridinecarboxylic) acid hydrazides (including isoniazid and fluvazide);
• Poliomyelitis (both in the acute phase and during the recovery period);
• Down syndrome.

In accordance with the instructions, Glutamic acid helps to improve the condition of patients who have suffered encephalitis or meningitis.

Contraindications

The use of glutamic acid is contraindicated in:

• Hypersensitivity to the drug;
• Functional insufficiency of the kidneys and / or liver;
• States that are accompanied by fever;
• Functional inferiority of the bone marrow (with depressed hematopoiesis);
• Increased excitability;
• Anemia;
• Characterized by the rapid flow of mental reactions;
• Gastric / duodenal ulcer;
• Obesity;
• Nephrosis (nephrotic syndrome);
• Leukopenia;
• Pregnancy and lactation.

Restriction to the use of funds, according to the instructions, are diseases of the kidneys and / or liver.

As for the use of glutamic acid in pediatrics, because of the tablet form, the drug is not indicated for children under 3 years of age.

Dosing and Administration

Glutamic acid should be taken orally approximately 15-30 minutes before meals, 2 or 3 times a day (if indicated).

A single dose is determined depending on the patient's age. For children of 3-4 years old, it is 250 mg, 5-6 years - 400 g, 7-9 years - 0.5-1 g, patients older than 10 years (including adults) - 1 g each.

With mental retardation (mental retardation), glutamic acid is taken within a few months at a dose of 0.1-0.2 g per kilogram of body weight.

The duration of treatment depends on the individual characteristics of the patient and the disease diagnosed in him. The course of treatment can last from 30 days to 1 year.

Side effects

The most likely side effects that may occur during the use of glutamic acid are:

• Allergic reactions (itching and hyperemia of the skin);
• Nausea;
• Vomiting;
• Abdominal pains;
• Loose stools;
• Increased excitability of the central nervous system.

In addition, doctors warn that prolonged use of the drug may cause a decrease in the concentration of hemoglobin, leukopenia, the appearance of cracks in the lips and irritation of the oral mucous membranes.

In case of development of any undesirable side effects during the period of treatment with Glutamic acid, it is recommended to stop the course and consult a doctor.

special instructions

Patients whose medication is accompanied by dyspeptic disorders, tablets should be taken with food or immediately after a meal.

During therapy with this drug, it is recommended to regularly perform general clinical analyzes of urine and blood.

To prevent or eliminate the neurotoxic effects associated with the use of drugs from the group of hydrazides g-pyridinecarboxylic acid (GINK-drugs), Glutamic acid can be used in combination with pyridoxine (vitamin B6) and thiamine (vitamin B1)

In case of myopathy and muscular dystrophy, it is advisable to prescribe the drug in combination with pahicarpine or amino acetic acid (glycine).

Glutamic acid tablets contain sugar, which should be remembered when prescribing them to patients with diabetes.

Given the possible effect of the drug on the nervous system, it should be taken with caution when driving a car and performing potentially dangerous types of work.

Analogs

The structural analogue of Glutamic Acid is Epilapton.

The following drugs are characterized by a similar mechanism of action: Heptor, Heptor N, Heptral, Histidine, Carniten, Carnitine, Elkar.

Terms and conditions of storage

Glutamic acid is a prescription drug. According to the instructions, it should be stored at room temperature (i.e. more than 25 ° C) in a place protected from sunlight. Shelf life of tablets is 4 years.