Glurenorm is a drug used in type 2 diabetes.
Release form and composition
Glurenorm is produced in the form of smooth white round-shaped tablets with beveled edges, on one side of which there is a risk and engraving “57С” on both sides of it, on the other - the company logo.
Each of them contains 30 mg of glycvidone and such excipients as:
- 5 mg of corn soluble starch;
- 134.6 mg of lactose monohydrate;
- 0.4 mg of magnesium stearate;
- 70 mg of dried corn starch.
Tablets are available in blisters of 10 pieces.
Indications for use
Glurenorm is prescribed to patients of middle and old age with diabetes mellitus type 2, with the ineffectiveness of diet therapy.
The use of Glurenorm is contraindicated in case of hypersensitivity to the components of the product, as well as in the following cases:
- Acute hepatic porphyria;
- Type 1 diabetes;
- Severe liver dysfunction;
- Diabetic ketoacidosis, precoma and coma;
- Conditions after resection of the pancreas;
- Pregnancy and during the period of lactation;
- Some acute conditions in which insulin therapy is indicated.
With caution Glurenorm prescribed for diseases of the thyroid gland, febrile syndrome, as well as patients suffering from alcoholism.
Dosing and Administration
Tablets are taken orally. The mode of receiving Glyurenorm and dosage means determined on the basis of indicators of carbohydrate metabolism.
Typically, the initial dose of the drug is half a pill, it is recommended to be taken during breakfast. Further, if necessary, gradually increase the dose (as recommended by the doctor).
In cases where the patient is prescribed 2 tablets per day, they can be taken in one step. Higher doses of Glyurenorm should be divided into two or three doses.
The instructions to Glurenorm indicate that the drug may cause side effects from some body systems, namely:
- Nausea, constipation, vomiting, loss of appetite, diarrhea, and intrahepatic cholestasis (digestive system);
- Dizziness, disorientation, and headache (nervous system);
- Leukopenia, thrombocytopenia and agranulocytosis (hematopoietic system).
Also, the drug can cause hives, eczema, pruritus and Stevens-Johnson syndrome.
With an overdose of the drug there is an increase in side effects. In such cases, it requires the abolition of Glurenorm and the appointment of calcitonin.
Hypoglycemic states are also possible with an overdose of an agent. When they occur, you must immediately enter the glucose (intravenously or orally).
If a rash, fever or nausea occurs during the use of Glurenorm, you should immediately consult a doctor.
The drug affects the ability to drive motor vehicles and complex mechanisms. In this regard, patients need to avoid potentially hazardous activities that require psychomotor speed and increased attention.
In cases where the development of allergic reactions is observed during the treatment with the agent, it is recommended to cancel Glyurenorm and replace it with insulin or another hypoglycemic agent.
It should be borne in mind that the hypoglycemic effect of the drug may increase with its simultaneous use with drugs such as:
- Phenylbutazone derivatives;
- MAO and ACE inhibitors;
- Anti-tuberculosis drugs;
- Tetracyclines and coumarin derivatives;
Glurenorm can be reduced by thyroid hormones, diazoxide, sympathomimetics, thiazide diuretics, glucocorticosteroids, oral contraceptives, glucagon, phenothiazine, and drugs that include phenytoin, nicotinic acid, rifampicin, and barbiturates.
Drug synonyms are not released. Glurenormo is related to analogues Maniglide, Glimepirid Canon, Chlorpropamid, Diabinaks, Glukostantabil and Amaryl.
Terms and conditions of storage
In accordance with the instructions, Glurenorm should be stored in a dark, dry and out of reach of children, at room temperature.
From pharmacies, the drug is released on prescription. The shelf life of tablets, subject to the recommendations of the manufacturer, is five years. Glurenorm cannot be used after the expiration date.