Hypoxen is an antihypoxant, antioxidant drug that reduces oxygen consumption and increases the body's performance (especially the heart, brain, liver) in extreme situations (hypoxia conditions).
Release form and composition
Hypoxen is available in the form of capsules and solution for injection, the main active ingredient of which is sodium polyhydroxyphenylene thiosulfonate.
As excipients in the preparation used:
- Capsules - titanium dioxide, gelatin, red iron oxide, black iron oxide, yellow iron oxide;
- Solution for injection - water for injection.
Hypoxen (capsules) can be produced in plastic bottles or cans of 30 capsules per pack, or in blisters of 20 or 30 pieces per pack; injection solution is available in 2 ml ampoules, 10 ampoules per package.
Indications for use
Hypoxen, according to the instructions applied:
- In the complex treatment of severe blood loss, injuries, diseases of the respiratory system (pneumonia, bronchial asthma, obstructive bronchitis), after extensive surgical interventions;
- With high physical and intellectual loads, with the performance of operator activities and other intense loads that lead to the development of fatigue and chronic fatigue;
- In order to improve performance in adverse environmental conditions, which are accompanied by a lack of oxygen (conditions of the Arctic, high mountains, underwater work, and others);
- In the complex treatment of stable angina with the aim of preventing attacks, chronic heart failure, arterial hypertension.
According to the instructions, Hypoxen is contraindicated in:
- The presence of a patient individual intolerance to the components of the drug;
- Hemorrhagic stroke;
- Pregnancy and lactation.
Dosing and Administration
Capsules Hypoxen, according to the instructions, are intended for oral administration. They are taken during a meal or before it starts, drinking water in small quantities.
A single dose of the drug is 2-4 capsules (0.5-1 g). The maximum daily dose depends on the weight of the patient and is:
- At 60-70 kg - 3-4 capsules;
- At 70-80 kg - 4-6 capsules;
- At 80-90 kg - 6-8 capsules;
- When 90-100 kg - 8-10 capsules;
- At 100-120 kg - 10-12 capsules.
The maximum daily dosage of the drug is 12 capsules.
With prolonged intense intellectual activity, chronic fatigue, in order to reduce the recovery period after injuries, excessive physical exertion, surgical interventions Hypoxen is taken 2 times a day at half the daily dose for 2-3 weeks with a repetition of a course of treatment after 1-2 weeks.
To eliminate hypoxia that develops in extreme conditions (playing sports, hypoventilation of the lungs, underwater work, high mountains, work at elevated temperatures), it is recommended to take Hypoxen half an hour before the loads in the amount of daily dosage.
With the treatment of pneumonia, the drug is taken twice a day at half the daily dose for 14 days.
In case of bronchial asthma, the drug is taken twice a day at half the daily dose for 21-30 days with an interval of 10 days.
With obstructive bronchitis, the drug is taken twice a day at half the daily dose in two courses of 14 days with a break of 7 days.
In order to prevent stable angina, Hypoxen is taken twice a day at half the daily dose in courses of 15-30 days with an interval of 10 days.
In case of heart failure, Hypoxen is taken twice a day at half the daily dose for 10-14 days.
In hypertension, the drug is taken twice a day at half the daily dose for 10 days.
Solution for injection Hypoxen is intended for intravenous administration (infusion rate of 40-60 drops per minute). The solution is injected for 3-6 days, 1-3 times a day, pre-dissolving the contents of the ampoule in 200-400 ml of 5% glucose solution or saline.
With the use of Hypoxen, adverse reactions of a predominantly allergic nature may develop (pruritus, erythema, hypotension). With too rapid intravenous administration of the drug can decrease blood pressure.
When using Hypoxen, it should be borne in mind that:
- With the development of allergic side reactions, the drug should be discontinued and the patient should be prescribed antihistamine drugs;
- An overdose of the drug is manifested by dry mouth, a feeling of discomfort in the stomach, nausea, and sometimes - respiratory depression. In such situations, the patient is shown gastric lavage followed by taking activated charcoal and prescribing symptomatic therapy;
- Too rapid intravenous administration of the drug should be avoided due to the possibility of hypotension.
The structural analogue of this drug is the drug Olifen.
Terms and conditions of storage
Hypoxen is stored at a temperature not higher than 25º in places with limited access for children, not more than two years.