Ginepriston is a postcoital oral contraceptive.
Release form and composition
Dosage form of the drug - tablets containing:
- 10 mg mifepristone;
- Additional components: 74.6 mg microcrystalline cellulose, 4.5 mg sodium carboxymethyl starch, 900 μg calcium stearate.
Ginepriston tablets are sold in 1 and 2 pcs. packaged.
Indications for use
In accordance with the instructions to Ginepriston, mifepristone - the active ingredient of this anti-progestogen - enhances the contractility of the myometrium, depending on the phase of the menstrual cycle, causes a change in the endometrium, delayed ovulation or prevents implantation of a fertilized egg.
Considering the described properties of the active component of Ginepristone, the drug is used for emergency post-coital contraception after unprotected sexual intercourse (or if the applied method cannot be considered reliable).
The use of Ginepriston contraindicated in:
- Acute or chronic renal / hepatic failure;
- The presence of severe extrageny pathology;
- Adrenal insufficiency;
- Long-term use of glucocorticosteroids;
- Hypersensitivity to mifepristone or any auxiliary component of the drug in history.
Apply the drug, but with extreme caution when:
- Chronic heart failure;
- Severe hypertension;
- The presence of a scar on the uterus;
- Myome of the uterus;
- Inflammatory diseases of the female genital organs;
- Chronic obstructive pulmonary diseases, including bronchial asthma;
- Violation of hemostasis, including the previous use of anticoagulants;
- Disorders of the heart rhythm.
The drug is contraindicated during pregnancy. But since it is intended for contraception, it is not necessary to take it during this period.
If emergency contraception is required during lactation, breastfeeding should be discontinued for 14 days after application of Ginepriston.
Dosing and Administration
According to the instructions to Ginepriston, the drug should be taken 1 tablet within 72 hours after unprotected intercourse.
To maintain the contraceptive effect of mifepristone, for 2 hours before taking it and for 2 hours after you should refrain from eating.
Ginepristone can be taken in any phase of the menstrual cycle.
According to reviews of women who took Ginepriston, in the vast majority of cases, this drug is well tolerated and does not have any serious side effects.
In some cases, the digestive system may respond to nausea and vomiting.
Possible reactions from the central nervous system are headache and dizziness.
Some women note that after the application of Ginepriston, bleeding from the genital tract appears, sometimes the menstrual cycle is disturbed.
In the presence of hypersensitivity to mifepristone or any auxiliary component of the drug may develop allergic reactions.
In isolated cases, complaints of hyperthermia, general weakness, and discomfort in the lower abdomen are received.
According to studies, when taking mifepristone in a dose of up to 2 grams, there are no symptoms of overdose. However, there is no need to exceed the dosage of the drug recommended in the instructions, because 10 mg is enough for a contraceptive effect.
In case of a significant excess of the drug dose, adrenal insufficiency is possible. There is no specific antidote for Ginepriston, treatment is symptomatic.
Every woman who chooses Ginepriston as a contraceptive should be informed that this drug does not protect against sexually transmitted diseases, including HIV and AIDS. In addition, it is not recommended to take as a permanent planned contraception.
If, after taking this remedy, menstruation is delayed by more than 5 days, or it starts on time and its course differs from the usual one, and also in cases when pregnancy is suspected, you should consult a doctor.
It is necessary to avoid situations where the simultaneous use of hypermine with non-steroidal anti-inflammatory drugs is required. Moreover, doctors say that NSAIDs should not be taken for at least 8 days after taking mifepristone.
Emergency contraception as a means of protection against unwanted pregnancies in adolescents is advisable to use only in special cases (for example, girls who have been raped) and always taking into account all the possible consequences.
Data on the negative impact of the drug on the ability to concentrate and the speed of psychophysical reactions are missing. However, we must not forget that one of the side effects of Ginepriston with potentially dangerous consequences is dizziness, therefore, it is recommended to be careful when driving a car and working with complex mechanisms.
Ginepriston's synonyms (i.e., structural analogues) are Agesta, Ginestril, Genale, Miropriston, Mifegin, Mifeprex, Mifepristone, Mifepriston-72, Mifolian, Pencrofton - all of them are available in the form of tablets for oral administration.
The same effect on the body has the drug Esmia.
Terms and conditions of storage
Ginepriston is a drug sold in pharmacies by prescription.
According to the manufacturer’s recommendations, it should be stored in its original packaging in a dark place at temperatures up to 30 ºС. Under these conditions, the shelf life of tablets - 3 years. Do not take after the specified storage period. Keep out of the reach of children!