Gepon - an immunomodulator with antiviral action.
Release form and composition
Dosage forms of the drug - 0.01% and 0.02% solution for ingestion and external use, as well as lyophilized powder for preparing a solution for oral and external use.
1 ml of 0.01% Gepon solution contains 1 mg of synthetic peptides consisting of 14 amino acid residues. This solution is implemented in bottles of 1 and 2 ml complete with a syringe or pipette.
1 ml of a 0.02% Gepon solution contains 200 μg of synthetic peptides. In pharmacies, the drug comes in bottles of 5 and 10 ml complete with a spray nozzle, a dropper cap, or a syringe.
Lyophilized powder Gepon is available in ampoules and vials of 1 and 2 mg, containing respectively 1 mg or 2 mg of the active substance.
Indications for use
The drug stimulates the production of antibodies to various antigens of an infectious nature, limits the production of inflammatory cytokines, inhibits the replication (introduction) of viruses, increases the body's resistance against infections caused by bacteria, viruses and fungi.
According to the instructions to Gepon, the drug is intended for:
- Correction of weakened immunity in people with immunodeficiency states;
- Enhance immune defense against infections;
- Treating HIV infection;
- Reduction of inflammation (pain, burning, swelling, itching, redness) and dryness of the mucous membranes and skin;
- The treatment and prevention of opportunistic infections caused by fungi, viruses and bacteria;
- Treatment and prevention of candidiasis of the mucous membranes and skin, including those developed as a result of antibiotic therapy.
In addition, the effectiveness of the use of Gepon with:
- Trophic ulcers due to varicose veins, diabetes, or radiation injuries;
- Acute respiratory diseases accompanied by signs of stenosing laryngotracheobronchitis;
- Acute intestinal infections;
- Acute and chronic viral hepatitis;
- Dermatitis of various origins;
- Chronic pharyngitis;
- Often recurrent respiratory infections;
- Chronic polypous rhinosinusitis;
- Mycoplasma, herpetic, chlamydial and other infections.
According to the results of clinical studies, the activation of local immunity against the background of the use of Gepon has a positive effect on the course of erosive and ulcerative lesions of the gastroduodenal zone. It can be used both as a mono-preparation, and as part of complex therapy in combination with omeprazole, trihopol or amoxicillin. In addition, this property of the drug is used in the treatment of dysbacteriosis and irritable bowel syndrome (in this case, Gepon is used in the form of microclysters).
The use of Gepon, according to the instructions, is contraindicated:
- Children up to 12 years;
- In case of hypersensitivity to the drug.
Dosing and Administration
The Gepon solution, including that prepared from a lyophilized powder (the lyophilisate is diluted with 5 ml of physiological saline or injection water), is intended for ingestion, external and topical administration.
Inside the drug is taken in a dose of 10 mg once a day. For the treatment of mucous membranes and skin using a 0.02-0.04% solution, the procedure is also carried out once a day.
For opportunistic and HIV infections, as well as other immunodeficiency states, the medicine should be taken orally. The duration of treatment is from 1 to 3 months.
For the prevention and treatment of diseases of the mucous membranes and skin caused by fungi of the genus Candida, Gepon solution is used in the form of irrigation of the affected areas. The general course of therapy usually involves carrying out three irrigations with an interval of 1-3 days.
For cervicitis, urethritis and vulvovaginal candidiasis in women, the drug is prescribed in the form of irrigation of the vagina, the mucous membrane of the vulva and cervix, and also in the form of lotions on the affected areas adjacent to the entrance to the vagina.
With balanoposthitis and candidal urethritis, instillations of Gepon into the urethra are made to men (drip injection of the drug into the urethra using a soft catheter of small diameter). In addition, the solution is used externally in the form of lotions to the affected skin.
For the prevention of candidiasis due to intensive antibiotic therapy, it is recommended to make lotions or irrigations with Gepon solution during antibiotic treatment.
To reduce the intensity of the inflammatory process, gauze napkins soaked in the preparation should be applied to the skin; mucous membranes should be irrigated with Gepon solution.
When using Gepon in recommended dosages, the drug does not have any side effects.
Structural analogues of Gepon no.
The following drugs belong to the same pharmacological group (“Immunostimulants”) and have a similar mechanism of action: Actinolizat, Anaferon, Arpetolid, Arpeflu, Affinoleykin, Bestim, Bioaron C, Broncho-Vax, Broncho-munal, Vilozen, Vitanam, Vobenzym, Galavit Herbion Echinacea, Glutoxim, Deoksinat, Dr. Theiss Echinacea Fortextras, Zaaxin, Izofon, Immunal, Immunal plus C, Immunex, Immunomax, Immunorm, Imudon, Imunorix, Imunofan, Imuron-vak, Copaxon-Teva, Methylutsyrats, Immunor, Imunofan, Imuron-vak, Copaxon-Teva, Methylutsyrats, Imunorix, Imunofan, Imuron-vak, Copaxon-Teva, Methylutsyrats, Immunor, Imunofan nucleinate, Neuroferon, P irogenal, Polyoxidonium, Poludan, KK Cat's claw, Rexodus, Ribomunil, Ruzam, Stemokin, Stemforte, Taktivin, Tamerit, Timaktid, Timalin, Tubosan, Uro-BCG, Uro-Vaks, Flogenzim, Floreksil, Ziklofer, Zurofer, Zikrofer, Uro-BCG, Uro-Vax Erbisol, Estifan, Echinacea, Ekhinatsin liquidum, Echinokor, etc.
Terms and conditions of storage
Gepon is a list B medication sold in a pharmacy by prescription prescribed by the attending physician.
The shelf life of the solution and the lyophilisate is 2 years, subject to the storage conditions recommended by the manufacturer - protected from direct sunlight at a temperature of 4 to 8 ºС.