Hepatrombin is an external combination drug that has anti-inflammatory, anti-thrombotic effects, and improves tissue regeneration.
Release form and composition
Make Gepatrombin in the form of a gel and ointment. The active components of the dosage forms are:
- Sodium heparin - an anticoagulant that prevents the formation of blood clots, has anti-inflammatory and anti-edema effects, improves local blood flow;
- Allantoin - stimulates the metabolism in tissues, has anti-inflammatory effect, promotes cell proliferation;
- Dexpanthenol - stimulates epithelization and granulation of tissues, improves the adsorption of heparin.
In addition to the above components, the composition of the gel Hepatrombin also includes essential oils that have analgesic and antimicrobial action.
Gel and ointment Gepatrombin produced in aluminum tubes of 40 g.
Indications for use
According to the instructions, Gepatrombin in the form of a gel and ointment is indicated for use for the prevention and treatment of the following conditions:
- Thrombophlebitis (inflammation of the wall of the vein, accompanied by the formation of a blood clot overlying the lumen of the vessel);
- Thrombosis (the formation of blood clots in the lumen of blood vessels);
- Varicose veins (expansion of the superficial veins of the lower extremities due to impaired blood flow and insolvency of the valvular apparatus);
- Sports injuries, accompanied by the formation of hematomas and bruises (sprains, bruises, etc.);
- Tendovaginitis (inflammation of the synovial membrane of the tendon).
Hepatrombin ointment can additionally be used to treat trophic leg ulcers resulting from circulatory disorders, as well as external inflammatory processes and seals on the skin (infiltrates), such as:
- Lymphangitis (inflammation of the walls of blood vessels);
- Mastitis (inflammation of the breast);
- Furuncle (purulent inflammation of the hair follicle with the involvement of the surrounding tissues);
- Carbuncleus (purulent inflammation of the sebaceous glands, hair follicles, surrounding skin and subcutaneous tissue).
According to the instructions, Gepatrombin should not be used in the following conditions:
- Open and infected wounds;
- Hypersensitivity to the active or auxiliary components of the drug;
- Violation of the integrity of the skin of any location (for the gel).
With caution, Gepatrombin is used in conditions accompanied by increased bleeding: thrombocytopenia, hemophilia, hemorrhagic diathesis.
Dosing and Administration
Hepatrombin applied to the affected skin with a thin layer with a frequency of 1-3 times per day. The gel is applied with light massaging movements from the bottom up. For thrombosis and thrombophlebitis, massaging is not recommended.
There are several ways to use Hepatrombin in the form of an ointment:
- For diseases of the veins that are not accompanied by thrombosis, the ointment is applied with light massaging movements in the direction of the natural outflow of blood through the veins (bottom to top). It is recommended to apply the drug in small quantities several times in a row;
- For thrombosis and thrombophlebitis, the drug is used in the form of dressings with ointment. At the same time, it is not recommended to massage the affected areas, as this may cause a thrombus to break off and it will begin to move freely through the blood vessels, causing a threat to the patient's life;
- For trophic ulcers, the ointment is applied in rings of 3-4 cm;
- For the treatment of carbuncles, boils ointment is used in the form of a gauze compress, which should be changed twice a day.
The use of Hepatrombin in most cases is positively tolerated by patients, side effects do not occur. Occasionally, the development of allergic reactions in the form of skin rash, itching, urticaria, angioedema, caused by hypersensitivity to the drug. In this case, the use of the medication should be discontinued and consult your doctor for the selection of alternative treatment.
During pregnancy and breastfeeding, the use of Hepatrombin is not recommended, except in cases where the potential benefit to the mother outweighs the possible risks to the fetus or child. For example, it is allowed to use Gepatrombin ointment for mastitis, which mainly develops during lactation. However, it is necessary to purchase a drug in which the content of heparin is not more than 300 IU in 1 g.
Data on overdose of Gepatrombin and its drug interactions are not provided.
The use of Hepatrombin does not affect the ability to control potentially dangerous mechanisms that require increased concentration of attention.
The structural analogue of Gepatrombin for the active ingredient is the drug Gepalpan.
Drugs with a similar mechanism of action and belonging to the same pharmacological group are: Agiolax, Aescin, Avenok, Aurobin, Gepatrombin G, Laxigal, Vazoket, Wencomfort, Papaverin, Ginkor Procto, Olestezin, Fayberleks, Prostotopin, Detraleks, Hypozol, Buteras, Bunthen, Hypozol, Bunthen, Apobine, Olestezin, Fayberleks, Prostotopin, Dipralex, Hypozol, Buntomfort , Tykveol, Rutin, Ethoxisclerol, Sulgan, Pramoxin, Dulcolax, Laxatin, Diavenor 600, Pyolysin, Proctosedil, Posterizan, Picosulfate, Relief Ultra, Romfalak, Simetrid, Phlebodia 600, Esculos, Proctof Glyuvenol, Glisthenol, Chestour, 600 galls, there is a short distance, and there is a short distance, and there is a simple way for you to use the current screen. Ride collection, Nefluan, Mukofalk, Metovit, Natalsid, Metrogil, Heferol.
Terms and conditions of storage
According to the instructions, Gepatrombin in the form of a gel and ointment should be stored in a place inaccessible to children, protected from moisture and exposure to direct sunlight, at a temperature of 15-25 ° C.
The shelf life of both dosage forms of the drug is 3 years.