Garamycin - a drug intended for the treatment of bacterial infections of the eyes and skin lesions, as well as infections of the central nervous system and respiratory tract.
Release form and composition
Drops Garamycin in the form of a colorless, transparent liquid, in dropper bottles of 5 ml.
One ml of the product contains 5 mg of gentamicin sulfate and excipients:
- 4.6 mg of sodium chloride;
- 14.33 mg of sodium dodecahydrate hydrogen phosphate;
- 0.2 mg of a 50% solution of benzalkonium chloride;
- 3.68 mg of sodium dihydrogen phosphate monohydrate;
- To 1 ml of purified water.
Another form of release of Garamicin is a solution intended for intravenous and intramuscular injections. Release the tool in 1 and 2 ml glass ampoules. 1 ml of the product contains 40 mg of gentamicin sulfate.
Also Garamycin released in the form of a cream and ointment for external use, 15 g in tubes. One gram of the product contains 1 mg of the active substance - gentamicin sulfate.
Indications for use
Garamycin in the form of eye drops is used in cases of bacterial infections of the eyes caused by sensitive microflora, namely when:
Ointment Garamycin is used for bacterial skin lesions.
The drug in the form of a solution is used to treat sepsis in newborns, infections of the gastrointestinal tract, urinary tract and kidneys, bacteremia, septicemia, gonorrhea and intraperitoneal infections.
Also, the agent is prescribed for infections of the central nervous system, respiratory tract, bones, skin, soft tissues, organs of vision and for perioperative prevention of infections.
The use of Garamicin of all forms of release is contraindicated in case of hypersensitivity to the components included in the preparation.
Eye drops are not prescribed to children under 1 year of age, in cases of myasthenia, severe renal dysfunction, neuritis of the auditory nerve, as well as during pregnancy and during the breastfeeding period.
Dosing and Administration
Garamycin eye drops in cases of infectious lesions of medium-sized eyes are instilled every 4 hours for 1-2 pieces. in the lower conjunctival sac, and in severe lesions - 1-2 pcs. every hour for 2 weeks.
The drug in the form of a solution used intravenously or intramuscularly. The dosage of Garamicin for adults depends on the disease, namely:
- In severe infections, 3 mg per 1 kg of body weight per day, divided into three equal portions and applied every 8 hours, or into two portions and administered every 12 hours;
- Patients with urinary tract infections with normal renal function are prescribed a single intramuscular injection of 240-280 mg Garamycin;
- In cases of infections where there is a high risk of death, 5 mg per 1 kg of body weight 3-4 times a day for 7-10 days. When clinical improvement is achieved, the dose is reduced to 3 mg / kg per day.
Garamicin solution for newborns up to 1 week, including premature infants, is 2.5 mg per 1 kg of body weight, used every 12 hours, for children over 7 days old, and infants, 2.5 mg per 1 kg of body weight every 8 hours, for patients older than 1 year - 6-7.5 mg / kg per day.
Also, the solution is used subconjunctivally at 10–20 mg per day and by inhalation, by endotracheal administration or spraying, for adults at 20–40 mg and for children at 15–30 mg every 8–12 hours per day. Before inhalation use, the agent is diluted with saline to obtain a volume of 2 ml.
Garamitsin ointment is applied externally, applying a thin layer of the agent to the affected area of the skin three or four times a day, with a possible application over the top of the dressing.
The instructions for Garamicin indicate that for several minutes after applying the installation, eye drops can cause eye redness, photophobia, tearing, burning and pain in the eyes.
With prolonged use of the drug in patients with hypersensitivity to the components that are included in its composition, in isolated cases hallucinations, thrombocytopenic purpura and allergic reactions have been observed.
Cream, ointment and injection Garamitsin can cause impaired renal function, as well as damage to the cochlear and predoor branches of the VIII pair of cranial nerves, which are expressed by the following side effects:
- Hearing loss;
- Numbness and tingling of the skin;
- Muscle twitching;
- Syndrome similar to Fanconi syndrome;
- Syndrome resembling malignant myasthenia.
In cases of aggravation of any of the above side effects, it is recommended to consult your doctor.
Due to the fact that the drug contains benzacolonium chloride, it is recommended to remove soft contact lenses before using Garamycin and install them no earlier than 15 minutes after the procedure. Such precautions are related to the fact that benzocolonium chloride can change the color of contact lenses and cause eye irritation.
After the drops are applied, blurring of vision is possible, therefore it is not recommended to dig Garamycin in the eyes before operating complex machinery or vehicles.
Therapy with the drug in the form of a solution for injection is important to carry out under constant monitoring of renal function, it is recommended to monitor the level of gentamicin in the blood. You should also consider the risk of respiratory paralysis and neuromuscular blockade.
The drug is synonymous with the drug Gentacicol. The analogue of Garamicin is the drug Gentamicin.
Terms and conditions of storage
Garamycin, according to the instructions, should be stored in a dry, well-ventilated, out of reach of children and protected from light, at a temperature varying between 2-30 ° C.
A medicine is released from a pharmacy by prescription; its shelf life is five years. After the expiration date of the drug must be disposed of.