Halidor - a drug intended for the treatment of diseases of the cardiovascular system.
Release form and composition
Halidor is produced in the form of round white flat tablets with a faint characteristic odor, with a facet and engraved “HALIDOR” on one of the sides in dark glass bottles of 50 pcs.
Each tablet contains 100 mg of benzikan fumarate and such excipients as:
- Magnesium stearate;
- Potato starch;
- Sodium carboxymethyl starch;
- Carbomer 934 P;
- Polyvinyl acetate;
- Silicon dioxide anhydrous colloid.
Halidor is also produced as a colorless, clear, odorless solution in 2 ml ampoules.
One vial contains 25 mg of benzkan fumarate and excipients - up to 2 ml of water for injection and 8 mg of sodium chloride.
Indications for use
Halidor is used in preparing patients for instrumental methods of research (in urology), as well as for the treatment of vascular diseases and the elimination of spasms of internal organs.
The use of Galidor is contraindicated in children under 18 years of age and in case of hypersensitivity to the components contained in the preparation. The drug is not prescribed during pregnancy and during the period of breastfeeding, as well as in cases of:
- AV blockade;
- Severe respiratory, hepatic, and renal failure;
- Recently suffered a hemorrhagic stroke;
- Acute myocardial infarction;
- Decompensated heart failure;
- Traumatic brain injury (during the last year);
- Epilepsy and other forms of spasmophilia;
- Paroxysmal supraventricular or acute ventricular tachycardia.
Dosing and Administration
The drug in the form of tablets is taken orally, the solution of Halidor is administered intravenously. Dosage means in cases of vascular disease is 1 tablet three times a day for 2-3 months, or injected 200 mg of the solution, divided into two doses. Before use, 4 ml of the product is diluted in 100-200 ml of isotonic sodium chloride solution.
For spasms of internal organs, patients take 1-2 tablets of Halidorus once.
In acute cases, 100-200 mg of the solution is administered intravenously slowly or deeply intramuscularly, 50 mg of the drug per day for 2-3 weeks. Next, patients, if necessary, transferred to the reception of the drug inside. Before intravenous administration, the amount needed is diluted with isotonic sodium chloride solution to obtain 10-20 ml.
The instructions to Halidor indicated that the drug may cause side effects from some body systems, namely:
- Headache, epileptiform seizures, symptoms of focal CNS damage, anxiety, gait disturbance, dizziness, tremor, memory disorders, insomnia, confusion and hallucinations (central nervous system);
- Abdominal pain, vomiting, feeling of satiety, nausea, dry mouth, diarrhea and loss of appetite (digestive system);
- Atrial and ventricular tachyarrhythmias (cardiovascular system).
Also, the drug can cause leukopenia, malaise, allergic reactions, thrombophlebitis and weight gain.
Symptoms of an overdose of Halidor are epileptiform seizures, increased heart rate, impaired kidney function, decreased blood pressure, urinary incontinence, collapse, anxiety, drowsiness, clonic and tonic convulsions.
In such cases, gastric lavage and the appointment of symptomatic treatment is required.
In cases of simultaneous use of Halidor with cardiac glycosides, drugs that cause hypokalemia or inhibit myocardial function, the daily dose of the drug should not exceed 150-200 mg.
Patients with respiratory or severe cardiovascular insufficiency, prostatic hypertrophy, urinary retention and collapse-prone are not recommended for parenteral administration of the drug.
At the beginning of drug therapy, patients should be careful when driving vehicles and conducting potentially hazardous activities.
Due to the fact that Halidor can cause thrombophlebitis and damage to the vascular endothelium, it is recommended to change the injection site in cases of parenteral use.
With long-term use of the drug is recommended at least 1 time in 2 months to conduct laboratory studies of the rheological properties of blood.
Drug synonyms are not released. Medicines Gliofen, Andekalin, Duzofarm, Vinkanor and Dibazol belong to the analogues of Halidor.
Terms and conditions of storage
Halidor, according to the instructions, should be stored in a dry, well-ventilated, out of reach of children and protected from light, at a temperature varying within 15-25 ° C.
Released from pharmacies drug by prescription. The shelf life of tablets Halidor is five years, the solution for injection is three years. After the expiration date of the drug must be disposed of.