Depantol is an antiseptic, tissue-stimulating drug used in dermatology, surgery, and gynecology. The preparation has antimicrobial activity against gram-negative and gram-positive bacteria, such as: chlamidia spp. protozoa (Trichomonas vaginalis). Individual strains of Proteus spp., Pseudomonas spp., And bacterial spores and acid-resistant forms of bacteria are resistant to Depanthol. Depanthol protects the wound surface from infection, accelerates healing.
Release form and composition
Depantol is available in the form of a cream and vaginal suppositories, the active substances of which are dexapanthenol and chlorhexidine digluconate (20% solution).
As auxiliary substances in Depanthol used:
- Macrogol cetostatearate cream, propylene glycol, stearyl alcohol, cetostearyl alcohol, liquid paraffin (medical vaseline oil), petrolatum, potassium dihydrophosphate, sodium hydrogen phosphate dodehydrate, purified water;
- Vaginal suppositories - macrogol 400, macrogol 1500.
The cream is available in aluminum tubes of 25, 30, 50 g, packed in a cardboard box. Vaginal suppositories - in a blister pack, 5 or 10 pieces per pack.
Indications for use
According to the instructions, Depantol in the form of a cream is used for:
- Treatment of postoperative wounds;
- Treatment of abrasions, scratches, cuts, scratching after insect bites, cracks, trophic ulcers, wounds after burns at the risk of infection;
- Treatment of bedsores, infected wounds, abrasions, burns (including solar), cracks, cuts, diaper rash, trophic ulcers;
- Treatment of diaper dermatitis, scratches with signs of infection in childhood;
- Treatments for atopic dermatitis and eczema;
- Treatment of cracks and inflammations of the nipples of the mammary glands with signs of infection in nursing mothers.
According to the instructions, Depantol in the form of vaginal suppositories is used for:
- Treatment of cervical erosion of a specific etiology as part of a combination therapy;
- Treatment of endocervicitis, exocervicitis, vaginitis;
- Improvement of vaginal and cervical mucosa regeneration after cryodestruction, diathermocoagulation, laser destruction, as well as in the postpartum and postoperative periods.
According to the instructions, Depantol is contraindicated for use if the patient has an increased sensitivity to the components of the drug.
Dosing and Administration
Cream Depantol designed for local external use. It is applied to the affected skin area with a thin layer one or several times a day.
When applying the cream in infants, it is applied to infected surfaces after water procedures or changing clothes.
When applying Depantol in the form of a cream in lactating women, it is applied to the skin of the nipple of the mammary gland after feeding.
Suppositories are intended for intravaginal administration. The drug is administered 1-2 times a day, one suppository. The duration of the course of treatment is 7-10 days. If necessary, the drug treatment is extended to 20 days.
When using Depantol in any dosage form, side effects may develop in the form of itching, burning, and allergic reactions.
When applying Depantol, it should be borne in mind that:
- The drug in the form of suppositories should not be used simultaneously with soap and detergents that contain an anionic group (sodium carboxymethylcellulose, saponins, sodium lauryl sulfate), which are administered intravaginally;
- It is possible to use Depantol during pregnancy and subsequent breastfeeding, but at the same time it is necessary to avoid applying the cream on large surfaces of the skin.
The structural analogue of this drug is Bepanten Plus.
Similar pharmacological effects have: Hexicon, Amident, Laveasept, Tsiteal, Chlorhexidine, Betadine, Dafnedzhin, Vagiflor, Hypozol, Iodoxide, Yodovidon, Laktozhinal, Jodosept, McMiror, Povidon-iodine, Macmiror complex, in a mode, and in a mode;
Terms and conditions of storage
Depantole is stored at a temperature not exceeding 25 ° in places not accessible to children, not more than two years.