Deca-Durabolin is a steroid injecting drug that has a high anabolic effect and a slight androgenic.
Release form and composition
Release Deca-Durabolin in the form of an oil solution for injection, in ampoules. An ampoule contains 25 or 50 mg of the active ingredient - nandrolone decanoate.
Indications for use
According to the instructions, Deca-Durabolin is indicated for use in:
- Muscular dystrophy;
- Diabetic retinopathy;
- Infantile atrophy;
- Conditions associated with calcium deficiency, caused by prolonged use of glucocorticosteroids, as well as due to postmenopausal or senile osteoporosis.
- With active catabolic processes, developing after carrying out complex operations and causing exhaustion;
- Against the background of chronic infections;
- With severe burns and injuries;
- With myopathy caused by taking glucocorticosteroids.
According to some data, Deca-Durabolin is effective for congenital aplastic anemia, as well as myelotoxic drugs developed as a result of bone marrow damage, heavy metal salts, malignant tumor metastases, bone marrow myeloid aplasia, myelofibrosis, myelosclerosis.
Deca-Durabolin is part of a comprehensive cytostatic treatment of malignant tumors, with the exception of inoperable carcinoma of the breast with the presence of metastases in women, which developed in the postmenopausal period or after removal of the ovaries, as well as prostate cancer. Also, Deca-Durabolin is included in the complex therapy of pituitary nanism in children and adolescents in cases where glucocorticosteroids have not had the desired effect.
According to the instructions, Deca-Durabolin is contraindicated in the following cases:
- Breast cancer in men;
- Prostate cancer;
- Breast cancer in women, complicated by the presence of metastases and excessive calcium in the body;
- Period of pregnancy and breastfeeding;
- Severe liver failure;
With caution steroid prescribed for:
- High blood pressure;
- Chronic heart failure;
- Heart attack;
- Prostatic hypertrophy;
- Chronic renal failure;
- Violation of cerebral circulation;
- Old age;
- Desk age up to two years;
- Hepatic insufficiency.
Dosing and Administration
For adult patients, Deca-Durabolin is injected intramuscularly in the buttock at a dose of 50 mg once every 3-4 weeks. If necessary, the dose may be increased to 100 mg. The duration of therapy is about one year, after which you need to take a month break.
For the treatment of breast cancer, refractory anemia and other serious conditions, a higher dose of Deca-Durabolin in combination with a protein diet may be required.
For the treatment of anemia, the steroid is indicated in combination with iron preparations. The dose for men is 100-200 mg once a week, women - 50-100 mg per week.
To stimulate the anabolic processes, Deca-Durabolin is prescribed to men once in 1-4 weeks at 50-200 mg each time, for women - at 50-100 mg each.
Children 2-3 years old Deca-Durabolin are taken once every 3-4 weeks at a dose of 25-50 mg.
In breast carcinoma, the drug is shown in 50-100 mg once a week. As an auxiliary treatment when performing cytostatic therapy, the drug is prescribed in a dose of 75 mg. In the same dose, medication is taken for anemia, which occurred on the background of chronic renal failure due to hyperazotemia.
In severe renal failure, Deca-Durabolin is taken in a dose of 50 mg once a week. At the time of drug therapy, you should monitor cholesterol, calcium, phosphorus, hematocrit, hemoglobin, blood glucose, as well as monitor the condition of the liver.
The use of Deca-Durabolin may cause the following side effects:
- Nausea, vomiting (including blood), epigastric pain;
- Iron-deficiency anemia;
- Impaired liver function;
- Decreased libido;
- Pain in tubular long bones;
- Increased activity of the sebaceous glands;
- Respiratory failure;
- Sleep disturbance;
- Dark Cal.
According to some reviews, the use of Deca-Durabolin can cause cholestatic hepatitis, symptoms of which are dark urine, discolored feces, pain in the right hypochondrium, yellow sclera.
In women, steroid therapy can cause dysmenorrhea, amenorrhea, clitoris enlargement, hoarseness, acne, and hair growth. If the drug treatment causes irregular menstruation, it should be stopped.
In adolescents, the use of Deca-Durabolin may cause enlargement of the penis, the formation of secondary sexual characteristics, prolonged and painful erection, slowing or stopping of growth, hyperpigmentation of the skin, and acne.
In men, the steroid can cause gynecomastia, irritation of the bladder, priapism, mastodynia, deterioration of sexual function.
In the case of taking the drug in excessively high doses, liver damage occurs. With the development of an overdose, the patient needs to do a gastric lavage and prescribe symptomatic treatment.
When the first signs of virilization appear, Deca-Durabolin therapy should be discontinued.
In cases of bone metastasis in breast carcinoma, before treatment with a steroid, calcium levels in the blood should be normalized. The drug can not be used as doping (for building muscle).
Structural and analogues and drugs with similar pharmacological action are:
Terms and conditions of storage
Deca-Durabolin stored in a cool place out of reach of children.