Buscopan is a drug that has a spasmolytic effect on the smooth muscles of internal organs and helps to reduce the secretion of the glands of the digestive tract.
Release form and composition
Buscopan is available in coated tablets and suppositories with the main active ingredient hyoscine-N-butyl bromide.
Auxiliary substances in the product are:
- Tablets - soluble starch, corn starch, dibasic calcium phosphate, tartaric acid, colloidal silicon dioxide, stearic / palmitic acid;
- Rectal suppositories - purified water, solid fat W45.
Buscopan tablets are available in blisters of 20 pieces per pack, suppositories - in strips of 10 pieces per pack.
Indications for use
According to the instructions, Buscopan is shown when:
- Biliary colic;
- Renal colic;
- Spastic dyskinesia of the gallbladder and biliary tract;
- Intestinal colic;
- Spasm of the ureter;
- Exacerbations of peptic ulcer, as part of complex therapy.
According to the instructions, Buscopan is contraindicated in:
- High patient sensitivity to the components of the drug;
- Angle-closure glaucoma;
- Pulmonary edema;
- Severe atherosclerosis of the cerebral vessels.
- Benign prostatic hyperplasia;
- Mechanical intestinal obstruction;
- Stenosis of the gatekeeper.
Buscopan is carefully prescribed for:
- Atrial fibrillation, ischemic heart disease, tachycardia, hypertension, mitral stenosis, acute bleeding;
- Reflux esophagitis;
- Elevated temperature;
- Paralytic intestinal obstruction;
- Hernia of esophageal orifice with reflux esophagitis;
- Intestinal atony in elderly and debilitated patients;
- Nonspecific ulcerative colitis;
- Urinary tract obstruction;
- Hepatic and renal insufficiency;
- Chronic lung diseases;
- Vegetative neuropathy;
- Urinary retention or predisposition to it;
- Toxicosis in pregnant women;
- Brain damage in children;
- Down's disease;
- Central paralysis in children;
as well as in patients over 40 years old.
Dosing and Administration
Buscopan in the form of tablets is intended for oral administration. Tablets washed down with water.
Suppositories are intended for administration to the rectum.
Buscopan dosage - 1-2 tablets or 1-2 suppositories 3 times a day.
When applying Buscopan may develop various side effects:
- Urinary system: urination, urinary retention;
- Organ of vision: accommodation paresis, mydriasis, increased intraocular pressure, blurred vision;
- Digestive system: constipation, nausea, vomiting, dryness of the mucous membranes of the mouth and nose, bloating;
- Allergic reactions: skin manifestations;
- Cardiovascular system: tachycardia, palpitations, increased blood pressure;
- Nervous system: headache, dizziness, weakness, nervousness, ataxia, agitation or confusion, speech disorder, memory impairment or amnesia, sleep disturbance;
- Other: decreased potency, decreased sweating.
When applying Buscopan, it should be borne in mind that:
The drug enhances the anticholinergic effect of antihistamines, tricyclic antidepressants, amantadine, quinidine, disopyramide;
The use of the drug simultaneously with dopamine antagonists (metoclopramide and others) weakens the effect on the digestive tract of both drugs;
The drug enhances beta-adrenergic tachycardia;
Despite the fact that there are no cases of Buscopan overdose, theoretically, symptoms of overdose can be manifested by urinary retention, reddening of the skin, dry mouth, depression of GI motility, tachycardia, transient visual impairment. In such cases, patients require gastric lavage with activated charcoal, and then with magnesium sulfate. For relief of symptoms of overdose using cholinomimetics. In the case of paralysis of the respiratory muscles, intubation and mechanical ventilation are used. With urinary retention, bladder catheterization is performed.
An analogue of Buscopan is Hyoscine butyl bromide.
Terms and conditions of storage
The drug is stored at a temperature of not more than 25º in places not accessible to children, not more than five years.