Budesonide is a drug used in the treatment of diseases of the respiratory system.
Release form and composition
Budesonide is released in the form of a substance-powder, in dark glass jars by half a kilogram. One dose of the drug contains 200 mcg of budesonide.
Also, the drug is released in the form of a metered aerosol, in 10 ml vials. Each vial contains 50 mcg of budesonide, which are designed for two hundred doses.
Indications for use
In accordance with the instructions, Bdesonide is used in the treatment of bronchial asthma and chronic obstructive pulmonary disease.
The drug in powder form is administered orally in cases of Crohn's disease, as well as intranasally with seasonal and year-round allergic rhinitis.
The use of budesonide in all forms of release is contraindicated in case of hypersensitivity to the components of the product. Powder Budesonide is not prescribed to children under 6 years old, suspension - under three months, solution for inhalation - at the age of 16 years.
With caution, budesonide is used during pregnancy, fungal, bacterial or viral infections of the respiratory system, tuberculosis, as well as during the breastfeeding period.
Dosing and Administration
Budesonide is used inhalation by cyclohaler, turbuhaler or any other special inhaler. It is important to bear in mind that one capsule of the inhaler contains 200 doses, and one detachable using a dispenser from a capsule with a powder portion - 200 μg of budesonide.
If the treatment of bronchial asthma previously used glucocorticosteroids or inhaled beta2-adrenostimulyatory, appoint one or two inhalation of budesonide twice a day.
In cases where systemic glucocorticosteroids were previously used to treat the disease, budesonide is prescribed at a dose of 400-800 mcg twice a day.
Children over 6 years old are prescribed 1-2 inhalations per day.
The instructions for budesonide indicate that the preparation in the form of an aerosol can cause the following side effects:
- Changes in the psyche, the formation of hemorrhages and tachycardia;
- Dysphonia, epistaxis and thrush;
- Irritation of the mucous membrane of the nasal cavity and pharynx, coughing and sneezing;
- Vomiting, oropharyngeal candidiasis, allergic reactions and fatigue;
- Dizziness, bronchospasm and stunting in children;
- Headache, thinning of the skin and perforation of the nasal septum;
- Anosmia, nausea and unpleasant taste sensations.
The use of budesonide in powder form during inhalation can cause sore throat, pharyngitis, paradoxical bronchospasm and cough. In cases of oral administration of budesonide powder, side effects may arise from various body systems, namely:
- Increased blood pressure, vasculitis and increased risk of blood clots (cardiovascular system);
- Cataract, euphoria, glaucoma, depression and irritability (sensory organs and nervous system);
- Aseptic bone necrosis, muscle weakness and osteoporosis (musculoskeletal system);
- Duodenal ulcer, pancreatitis, epigastric pain and dyspeptic symptoms (gastrointestinal tract);
- Ecchymosis, red striae, petechiae, allergic rash, steroid acne, impaired wound healing and contact dermatitis (skin);
- Diabetes mellitus, obesity, decreased glucose tolerance, Cushing's syndrome, hirsutism, atrophy or decreased function of the adrenal cortex, sodium retention with the formation of edema, hypokalemia, impotence, and amenorrhea (endocrine organs).
Intranasal application of budesonide powder can cause the appearance of candidosis, sneezing, burning and irritation of the nasal mucosa.
During the direct use of the drug, it is important not to allow it to get into the eyes.
The efficacy and safety of budesonide in children under the age of 6 years have not yet been determined. Studies have shown that large doses of the drug can slow the growth rate and cause a decrease in the secretion of hydrocortisone in children over 6 years of age, therefore during the period of therapy it is recommended to monitor these indicators regularly.
Due to the fact that when it enters the oral cavity, the remedy may contribute to the development of candidal stomatitis, it is important to rinse your mouth thoroughly after each use.
The bottle of Budesonide should not be frozen, taken apart, exposed to direct sunlight, pierced and thrown into the fire.
When cooling the spray can, it is recommended to remove it from the body before use and warm it up with your hands.
The drug synonyms are Budieir, Tafen Novolizer, Benacort, Budenit, Steri-Neb, Budecort, Novopulmon E Novolizer and Pulmicort.
Such medicines as belong to analogs of Budesonide:
- Beclazon Eco;
- Asmanex Twistheiler;
- Klenil UDV;
Terms and conditions of storage
Budesonide, according to the instructions, should be stored in a dry, well-ventilated place, out of the reach of children and light, at a temperature varying within 15-25 ° C.
A medicine is released from a pharmacy by prescription; its shelf life is five years. After the expiration date of the drug must be disposed of.