Bromocriptine is a drug used in the treatment of Parkinson's disease, female infertility and hyperprolactinemia in men.
Release form and composition
In accordance with the instructions, Bromocriptine is produced in the form of flat white tablets, on one side of which there is an engraving "2.5", and on the other risk, in blisters of 10 pieces.
Each tablet contains 2.5 mg of bromocriptine and the following excipients:
- Microcrystalline cellulose;
- Magnesium stearate;
- Corn starch;
- Lactose monohydrate;
- Silicon dioxide anhydrous colloid.
Indications for use
The instructions for bromocriptine indicate that the drug is prescribed to patients with Parkinson's disease, female infertility, menstrual disorders, premenstrual syndrome, prolactinoma, hyperprolactinemia (men), as well as to suppress lactation and treatment of benign breast diseases.
Bromocriptine is contraindicated for familial and essential tremor, Huntington's chorea, toxicosis during pregnancy, endogenous psychosis, severe cardiovascular diseases, hypotension, as well as in cases of hypersensitivity to the components of the drug and hypertension in the postpartum period.
Dosing and Administration
The drug is taken orally during the meal. The doctor defines a dosage of means in an individual order. It usually ranges from 1.25 to 2.5 mg of bromocriptine, taken two or three times a day. In cases of parkinsonism, the daily dose of the drug is gradually increased by 10-40 mg, and for acromegaly, prolactinoma, benign breast diseases and hypogonadism - by 5-20 mg.
In cases where, when selecting the individual dosage of bromocriptine in a patient, the side effects of therapy occur, it is recommended to reduce the dose to keep it at that level for a week. After the side effects have completely disappeared, the dose can be gradually increased.
The instructions to bromocriptine indicate that the agent can cause cramps in the calf muscles, nasal congestion, skin rashes and side effects from some body systems, namely:
- Dyskinesia, decreased visual acuity, headache, drowsiness, hallucinations, psychomotor agitation and dizziness (central nervous system);
- Orthostatic hypotension, arrhythmia and Raynaud's syndrome (cardiovascular system);
- Impaired liver function, dry mouth, diarrhea, constipation, nausea and vomiting (digestive system).
Patients at the beginning of treatment one hour before the first use of bromocriptine is recommended to take an antiemetic.
Due to the fact that during therapy with the drug, hypotensive reactions can occur, during the first few days of treatment, blood pressure should be monitored regularly.
In patients with a regular menstrual cycle with long-term therapy with Bromocriptine, it is recommended to perform a gynecological examination once a year, including a cytological examination of endometrial and cervical tissues. In cases of menopause, a similar survey is carried out regularly once a month for six months.
The side effects arising during drug therapy diminish or disappear completely after a reduction in the dose taken.
In cases of pituitary adenoma, accompanied by a significant increase in the size of the Turkish saddle and violation of visual fields, the use of bromocriptine is permissible only when a positive effect was not achieved after surgical treatment and radiation therapy.
It is important to warn patients in advance that during the period of drug treatment one should refrain from conducting potentially hazardous activities that require quick psychomotor reactions and increased attention.
The drug is synonymous with drug Bomergon. Analogues of bromocriptine are medicines Pravidel and Parlodel.
Terms and conditions of storage
Bromocriptine, according to the instructions, should be stored in a dry, well-ventilated, out of the reach of children and light place, at a temperature not exceeding 30 ° C.
The drug is released from pharmacies by prescription, its shelf life is three years. After the expiration date of bromocriptine must be disposed of.