Betak - a drug with antihypertensive, antiarrhythmic and antianginal actions.
Release form and composition
Betak is produced in the form of tablets and eye drops, the main active ingredient of which is betaxolol hydrochloride.
As excipients in tablets used: sodium starch glycolate, lactose monohydrate, anhydrous colloidal silicon, microcrystalline cellulose, magnesium stearate, titanium oxide, hydroxypropylmethylcellulose, polyethylene glycol 400.
Tablets are available in blister packs of 30 pieces per pack; eye drops - in bottles with a dispenser of 5 ml.
Indications for use
According to the instructions, Betak in the form of tablets is used for:
- Hypertrophic cardiomyopathy;
- Akathisia due to the administration of antipsychotics;
- Coronary heart disease;
- Cardiac rhythm disorders (arrhythmias on the background of mitral valve prolapse and thyrotoxicosis, sinus tachycardia, extrasystole, ventricular and supraventricular tachyarrhythmia).
According to the instructions Betak in the form of eye drops is used for:
- Intraocular hypertension;
- Chronic open-angle glaucoma;
- States after laser trabeculoplasty;
- Long-term antihypertensive therapy after ophthalmic surgery.
According to the instructions, Betak is contraindicated in:
- Patient hypersensitivity to the drug;
- Chronic heart failure II-III degree;
- Acute heart failure;
- Atrioventricular block II-III degree;
- Cardiogenic shock;
- Syndrome of weakness of the sinus node;
- Sinoatrial blockade;
- Bradycardia with a heart rate of less than 40 per minute;
- Printsmetal angina pectoris;
- A history of anaphylactic reactions;
- Severe bronchial asthma;
- Severe Raynaud syndrome;
- Congenital galactosemia, glucose-galactose malabsorption syndrome, lactase deficiency;
- Pregnancy and lactation;
and also in childhood.
Betak is carefully used for:
- Obliterating diseases of peripheral vessels;
- Chronic renal and hepatic impairment;
- Metabolic acidosis;
and also in old age.
Dosing and Administration
Betak tablets are intended for oral administration. They are taken at any time of the day, regardless of the meal.
- The average daily - 20 mg;
- The maximum daily - 40 mg;
- In hypertension, 10 mg once a day. After 7-14 days, dosage may be increased to 20 mg per day;
- For elderly patients and patients with severe renal insufficiency who are on hemodialysis or peritoneal dialysis, 5 mg per day with a possible further increase in dosage;
Eye drops are applied one drop to the affected eye 2 times a day with constant monitoring of intraocular pressure in the first month of treatment.
When Betaka is used, certain adverse reactions may develop:
- Cardiovascular system: AV blockade, bradycardia, orthostatic hypotension, heart failure, deterioration of peripheral circulation;
- Nervous system: asthenia, headache, dizziness, drowsiness, insomnia, depression, paresthesia, neuropathy, neuralgia, tinnitus, tremor;
- Urogenital system: dysuria, oliguria, impotence, menstrual disorders, proteinuria, edema, cystitis, renal colic, decreased libido, prostatitis;
- Digestive system: dyspepsia, dry mouth, nausea, diarrhea, anorexia, vomiting, dysphagia;
- Respiratory system: bronchospasm, sinusitis, shortness of breath, rhinitis, cough;
- Allergic reactions: urticaria, skin rash, itching;
- Others: myalgia, eczema, erythema, exacerbation of psoriasis, hyperglycemia, acidosis, hyperkalemia, hypercholesterolemia, change in body weight, hypothermia.
When using Betakav as eye drops, dry eye, lacrimation, discomfort and foreign body sensation in the eye, photophobia, blurred vision, keratitis, pain, anisocoria, erythema, pruritus, patchy cornea staining, corneal sensitivity, systemic reactions can occur.
When applying Betaka should be borne in mind that:
- In the early days of drug treatment, heart failure may develop;
- The drug can mask the symptoms of hypoglycemia, so when it is taken by patients with diabetes, it is necessary to constantly monitor blood sugar levels and heart rate. If bradycardia occurs, the dosage of the drug is reduced or canceled;
- In COPD and bronchial asthma, the drug is prescribed only in low initial dosages with a preliminary determination of the function of external respiration;
- The effectiveness of drug treatment can be controlled after 3-4 weeks from the moment of its beginning;
- The drug should be canceled no less than 48 hours before the upcoming surgery using anesthesia;
- The drug is canceled gradually (reducing the dosage) within 7-14 days;
- Taking Betaka simultaneously with neuroleptics or nifedipine may cause orthostatic hypotension;
- The hypotensive effect of Betaka is weakened by NSAIDs and estrogen-containing agents;
- The drug increases the concentration of lidocaine in the blood plasma;
- When taking the drug simultaneously with reserpine increases the risk of hypotension and bradycardia;
- An overdose of the drug is manifested by bradycardia, syncope, atrioventricular block, bronchospasm, a drop in blood pressure, convulsive syndrome, arrhythmia, heart failure, cyanosis of the palms and nails, and ventricular extrasystole. In such situations, gastric lavage is required, followed by the intake of adsorbents and symptomatic therapy.
Analogs of Betaka are Betaxolol, Betoptik, Betalmik, Xonef, Beofthan, Lokren, Optibetol.
Terms and conditions of storage
The drug is stored at a temperature of 15-25º in places with limited access of children no more than two years.