Besalol is an intestinal antiseptic that is used for functional disorders of the stomach and intestinal tract. The drug belongs to the pharmacotherapeutic group "Antispasmodics and anticholinergics in combination with other drugs."
Release form and composition
Available in the form of tablets, packaged in 6 pieces in contour without cell packaging.
The composition of one tablet includes 10 mg of extract of the leaves of belladonna (belladonna) thick and 300 mg of phenylsalicylate. As auxiliary components in the production process of Besalol are used:
- Microcrystalline cellulose;
- Lactose monohydrate;
- Croscarmellose sodium;
- Stearic acid.
Indications for use
According to the instructions for Besalol, the use of this drug is indicated for diseases of the stomach and intestines, which are accompanied by spasms of smooth muscles of the abdominal organs and intestinal dysbacteriosis. In particular, it is used for colitis (inflammation of the internal mucous membrane of the large intestine), enteritis (inflammation of the small intestine) and enterocolitis (inflammation of both the small and large intestine).
The use of Besalol is prohibited if a patient has:
- Angle-closure glaucoma;
- Benign prostatic hyperplasia (adenoma) of the prostate gland;
- Bleeding in any part of the digestive tract;
- Individual sensitivity to the components of the drug.
Due to the lack of data on the safety of Besalol in pediatrics, the drug should not be taken in children and adolescents under 18 years of age.
The composition of Besalol includes lactose, and therefore the drug is prescribed with caution to patients with:
- Hereditary lactose intolerance;
- Impaired glucose / galactose absorption;
Dosing and Administration
For adults, Besalol is recommended to take 1-2 tablets two or three times a day. The maximum permissible daily dose should not exceed 6 tablets.
The optimal dosage of the drug and the duration of treatment are determined depending on the severity of the disease, the severity of the symptoms accompanying it, the patient's response to the prescribed therapy, and the nature of the therapy (taking Besalol as a monotherapeutic agent or in combination with other drugs).
The instructions to Bezalol indicate that in some patients taking the drug may cause:
- Neurological disorders (eg, increased dry mouth);
- Disorders of the organs of vision (increased intraocular pressure, medical mydriasis, paralysis of the ciliary muscle of the eye);
- Urinary retention;
- Reactions from the immune system (in particular, allergic reactions, which are expressed in the form of rashes on the skin).
If any side effects occur, stop taking the medication and contact a medical institution.
A minor overdose of Besalol can manifest itself with the following symptoms:
- Disturbance of accommodation of the eyes;
- Difficulty urinating;
- Decreased muscle tone of the intestinal tract;
- Dysphagia, which is manifested by pain and difficulty swallowing;
- Skin rashes.
Significant excess of the recommended dose of Besalol can cause an increase in intraocular pressure, dry skin and mucous membranes, mydriasis, accommodation paralysis, an increase in the frequency of cardiac muscle contractions, urinary retention, increased mental and physical activity, delirium (quality disorder of consciousness), seizures.
Treatment involves the abolition of the drug and the appointment of symptomatic therapy. Antidotes besalola are Prozerin and physostigmine.
The safety of Besalol use during pregnancy and lactation periods has not been established; therefore, women in the situation, especially in the first and second trimesters, are prescribed only when alternative therapy is not possible, while taking into account the ratio of the expected benefits for the expectant mother and possible risks. for the developing fetus. In consultation with the doctor who leads the pregnancy, the use of Besalol tablets in the third trimester of pregnancy is allowed.
Breastfeeding for the period of drug treatment is recommended to stop.
It should be borne in mind that belladonna alkaloids can affect the results of laboratory studies such as:
- The test for the determination of gastric acidity (alkaloids can counteract the activity of pentagastrin and histamine);
- Radioisotope study of gastric emptying (can slow down this process);
- Phenolsulfoftaleinovy test urine secretion (can slow down the excretion of phenolsulfonphthalein in the urine).
The pharmacological action of decongestant alkaloids can be enhanced with the simultaneous use of other drugs with an antimuscarinic effect, including amantadine, tricyclic antidepressants, phenothiazines, butyrophenone derivatives.
Patients undergoing treatment with Besalol should refrain from controlling vehicles, performing work associated with risks to health and life, as well as tasks requiring increased concentration of attention and speed of psychomotor reactions.
Analogues of Besalol are belladonna drugs, similar in mechanism of action - Bellastezin, Gazospazam, Movaspasm, Bekarbon, Gastropin, Gastric drops.
Terms and conditions of storage
Besalol is a drug released from pharmacies in non-prescription mode. According to the instructions, these tablets should be stored in their original packaging in a dry place protected from sunlight. The optimum storage temperature is from 8 to 15 ºС.
The drug retains its pharmacological properties for 4 years. After this period, you cannot use Besalol.