Bagomet is a hypoglycemic drug.
Release form and composition
Make Bagomet tablets containing the active ingredient - metformin hydrochloride - in an amount of 500 mg.
Medications include povidone, croscarmellose sodium, lactose monohydrate, corn starch, stearic acid.
In blister packs of 10 tablets.
Indications for use
According to the instructions, Bagomet is indicated for diabetes mellitus type 2 without a tendency to ketoacidosis, in particular in patients with obesity and with the ineffectiveness of diet therapy.
According to the instructions, Bagomet is contraindicated in:
- Severe renal dysfunction;
- Diabetic ketoacidosis;
- Diabetic precoma, coma;
- Pregnancy and lactation;
- Respiratory and heart failure, myocardial infarction in the acute stage, dehydration, impaired cerebral circulation, chronic alcoholism and other conditions conducive to the development of lactic acidosis;
- Hypersensitivity to the active or auxiliary components;
- History of lactic acidosis;
- Acute alcohol poisoning;
- Impaired liver function;
- Injuries and surgical interventions involving insulin therapy;
- Observe a low-calorie diet (less than 1000 calories per day);
- The use of 2 days or within 2 days after x-ray or radioisotope studies with the introduction of iodine-containing contrast agent.
The use of Bagomet is not recommended for patients over 60 years of age, as well as those engaged in heavy physical work, since there is a high risk of developing lactic acidosis in them.
Dosing and Administration
Bagomet is intended for oral administration.
The dosage of the drug is set individually, depending on the blood glucose level.
The initial dose of Bagomet is 1-2 tablets with a further gradual increase in 10-15 days (depending on the level of glycemia).
Maintenance dose of Bagomet is 3-4 tablets per day, the maximum daily - 6 tablets.
For elderly patients, the daily dosage of the drug is 2 tablets.
Tablets are taken whole with a meal or immediately after it, with a glass of water.
In severe metabolic disorders, the dose of Bagomet is recommended to be reduced in order to avoid the development of lactic acidosis.
The use of Bagomet can cause the following side effects:
- Metabolism: lactic acidosis (this is a side effect requires the abolition of Bagomet), lack of vitamin B12 due to malabsorption;
- Digestive system: nausea and vomiting, loss of appetite, abdominal pain, flatulence, metallic taste in the mouth, diarrhea;
- Hematopoietic system: megaloblastic anemia;
- Endocrine system: hypoglycemia (when used in high dosages);
- Allergies: skin rash.
In case of an overdose Bagomet can cause the development of lactic acidosis with a fatal outcome. The reason for this is the accumulation of the drug due to impaired renal function.
Symptoms of lactic acidosis are:
- Stomach ache;
- Lowering body temperature;
- Rapid breathing;
- Impairment of consciousness;
If the above symptoms appear, the drug should be immediately discontinued, and an ambulance should be called. In the hospital, the patient will determine the level of lactate and hemodialysis, as well as symptomatic therapy.
With the combination of Bagomet with acarbose, sulfonylurea derivatives, nonsteroidal anti-inflammatory drugs, monoamine oxidase inhibitors, clofibrate derivatives, angiotensin-converting enzyme inhibitors, beta-adrenoblockers, cyclophosphamide, its hypoglycemic action may increase.
With the simultaneous use of Bagomet with oral contraceptives, glucocorticosteroids, sympathomimetics, epinephrine, thyroid hormone preparations, glucagon, phenothiazine derivatives, nicotinic acid derivatives, it is possible to reduce its hypoglycemic action.
Cimetidine in combination with Bagomet increases the risk of lactic acidosis.
It is not recommended to combine Bagomet with alcohol-containing drinks, as this increases the risk of developing ketoacidosis.
Patients should be monitored for kidney function during Bagometry therapy. Twice a year, as well as the appearance of myalgia, it is recommended to determine the plasma content of lactate.
Bagomet may be used in combination with sulfonylurea derivatives, but only under careful control of blood glucose levels.
Analogs of Bagomet are the following drugs:
- Formin Pliva;
- Diaformin OD;
- Nova Met;
Terms and conditions of storage
According to the instructions, Bagomet refers to the list of drugs B. Store the medicine should be in a dark, dry, out of reach of children. Shelf life - 2 years.