Aspirin belongs to the group of nonsteroidal anti-inflammatory drugs.
Release form and composition
In pharmacy chains, the drug is presented in the form of tablets, the main active ingredient of which is salicylic acid. In one pill its content is 100 or 500 mg. Tablets are white, beveled edges, their shape is biconvex. On one side there is an impression in the form of a Bayer logo, on the other - the inscription “Aspirin 0.5”.
Auxiliary substances in the composition of the drug are corn starch and microcrystalline cellulose.
Tablets with the content of acetylsalicylic acid in 100 mg in an amount of 10 pieces are packed in contour cells and sealed in cardboard boxes. Tablets with 500 grams of the substance in the same quantity are packaged in blisters. In one cardboard pack there are 1, 2 or 10 blisters.
Indications for use
Aspirin is recommended for use to alleviate the symptoms of headache, toothache, and other types of pain (in the throat, during menstruation, in muscles and joints, in the back). Also, the use of Aspirin is advisable at elevated body temperature in infectious and inflammatory diseases in adults and children over 15 years.
The instructions for Aspirin list of diseases for which you should refuse to take the drug:
- Hemorrhagic diathesis;
- Erosive and ulcerative diseases of the gastrointestinal tract in the acute phase;
- Bronchial asthma caused by taking NSAIDs (including salicylates).
In addition, the use of Aspirin is not recommended for pregnant women (1 and 3 trimesters), women during lactation, people with hypersensitivity to the components of Aspirin, as well as patients taking methotrexate in a dose of more than 15 mg per week.
The therapy of acute respiratory diseases caused by viral infections with Aspirin in children under 15 years of age is prohibited due to the high probability of developing Reye's syndrome (encephalopathy and acute fatty liver).
With care, Aspirin is prescribed for gout, taking anticoagulants, hyperuricemia, gastrointestinal ulcer, nasal polyposis, bronchial asthma, chronic diseases of the bronchi or lungs, for disorders of the kidneys or liver, in the second trimester of pregnancy.
Dosing and Administration
The dosage is selected depending on the type of disease and the severity of its symptoms.
Thus, in case of weak or medium pain syndrome, as well as in febrile conditions, the single dose recommended in the Aspirin instructions is 0.5–1 g of the drug; the maximum single dose is 4 grams. Between doses, 4-hour intervals should be observed. The maximum daily dose is 6 tablets or 3 g of aspirin.
Tablets are taken orally, after meals, with a necessary amount of liquid.
It is not recommended to take the medication without a medical prescription for more than 7 days as an anesthetic, and more than 3 as an antipyretic.
The side effects of the gastrointestinal tract indicated in the Aspirin instructions are as follows: vomiting, heartburn, nausea, abdominal pain, increased liver enzymes; signs of gastric bleeding (both overt and covert) that can cause iron deficiency anemia, erosive and ulcerative lesions of the gastrointestinal tract.
CNS may experience tinnitus and dizziness, which usually indicate an overdose of acetylsalicylic acid.
Among the allergic reactions may appear urticaria, anaphylactic shock, angioedema, bronchospasm.
May increase the duration of bleeding.
The use of Aspirin can provoke the occurrence of bronchospasm, an attack of bronchial asthma, other hypersensitivity reactions in connection with acetylsalicylic acid contained in it. Risk factors are a history of bronchial asthma, fever, nasal polyps, chronic lung and / or bronchial diseases, and a history of allergies (including allergic rhinitis, skin rashes).
Acetylsalicylic acid increases the tendency to bleeding, which is associated with its feature of inhibiting platelet aggregation. In this regard, it is necessary to cancel the reception of Aspirin for 5-7 days before surgery, to prevent increased bleeding during and after surgery.
Patients with gout need to consider the ability of acetylsalicylic acid to reduce the excretion of uric acid from the body, which can trigger an acute attack of gout.
Below is a list of drugs, the mechanism of action and the composition of which are close to those of Aspirin:
- Upsarin Upsa et al.
Terms and conditions of storage
As noted in the instructions for Aspirin, the drug is valid for 5 years from the date of issue.
It is recommended to store the drug at a temperature not exceeding the 30-degree mark, out of the reach of children.