Ascorbic acid is a vitamin that is involved in redox processes in the body, the metabolism of a number of substances, the formation of collagen, and the strengthening of bone structures.
Release form and composition
The drug is available in several dosage forms:
- Powder for the manufacture of a solution for oral administration, packaged in 2.5 g, 1 g packages, 1 g. In one package there are 10 or 100 packages;
- Tablets for oral administration weighing 25, 50.75, 200, 300, 500 mg. The number of tablets in one package: 10, 20, 30, 40, 100 or 200 pieces;
- Drops weighing 50 mg in an amount of 200 pieces per pack;
- Solution for in / in or in / m introduction in ampoules.
Indications for use
Ascorbic acid in combination with other drugs is used in the treatment and prevention of vitamin C hypo-and avitaminosis, in case of an increased need of the body for ascorbic acid during lactation, pregnancy, during intensive growth, with high physical exertion, overwork, recovery after long diseases, and also during the winter period and the period of epidemics of catarrhal diseases.
Intravaginal application of ascorbic acid is recommended for vaginitis in a chronic or recurrent form, of bacterial or nonspecific genesis for the restoration of impaired vaginal microflora.
Persons with hypersensitivity to ascorbic acid, as well as patients with thrombophlebitis or a tendency to it should not be taken.
Dosing and Administration
Vitamin C is administered intravaginally, orally, intramuscularly or intravenously.
Recommended in the instructions for ascorbic acid dosage for oral administration is from 50 to 100 mg per day. The maximum single dose should not exceed 0.2 g, and daily - 0.5 g of the drug.
If another method of administration as prophylaxis of hypo-and avitaminosis should be applied from 25 to 75 mg per day, for treatment - not more than 250 mg.
Adverse reactions possible during use of ascorbic acid:
- Allergic skin rashes;
- Feeling tired, headache, insomnia;
- Nausea, stomach cramps, vomiting;
- Hyperoxaluria, the formation of kidney stones from calcium oxalate (in the case of the use of vitamin in high doses);
- Burning, itching in the vagina, hyperemia, increased mucous secretions, swelling of the vulva (with intravaginal administration);
- Feeling hot.
The drug is used with caution in patients with hyperoxaluria, with impaired renal function, urolithiasis.
Due to the fact that vitamin C enhances the absorption of iron, the use of ascorbic acid in high doses by patients with thalassemia, hemochromatosis, leukemia, polycythemia, sideroblastic anemia is not recommended.
Vitamin supplementation in low doses is recommended for people with high iron levels in the blood.
Patients with glucose-6-phosphate dehydrogenase deficiency are advised to take ascorbic acid with caution.
The use of ascorbic acid in sickle cell anemia can cause its aggravation.
According to some reports, long-term intake of vitamin C can provoke an increase in the level of glucose in the blood; therefore, during the period of its long-term use, monitoring of glucose indicators is recommended.
It is necessary to use the drug with caution in patients with advanced cancer, because there is evidence of the ability of the vitamin to aggravate the process of tumor growth.
The process of absorption of ascorbic acid slows down when it is consumed simultaneously with fresh fruit, vegetable juices or alkaline drinks.
The minimum daily requirement for vitamin C during pregnancy is about 60 mg.
Ascorbic acid is able to penetrate the placental barrier, so you should strictly adhere to the recommended doses, otherwise ascorbic disease may develop in the newborn.
During lactation, the minimum recommended dose per day is 80 mg. At the same time, the instructions for ascorbic acid indicate that excessive consumption of vitamin C can be theoretically dangerous for the newborn.
An analogue of ascorbic acid are Upsavit vitamin C tablets.
Terms and conditions of storage
Ascorbic acid is recommended to be stored in a dark and dry place, where the temperature is not higher than 25 degrees.
The shelf life of the drug is 24 months.