Ambrogexal belongs to the group of expectorant and mucolytic drugs.
Release form and composition
Ambrohexal is produced in the form of tablets, oral solution and preparation of inhalations, and in the form of capsules of prolonged action. In the composition of the drug active active ingredient - ambroxol hydrochloride, as well as the following auxiliary components:
- In tablets: calcium hydrophosphate dihydrate, lactose monohydrate, corn starch, magnesium stearate, colloidal silicon dioxide;
- In capsules: Eudragid RL30D, MCC, triethyl citrate, titanium dioxide, magnesium stearate, Eudragid RS30D;
- In solution: citric acid, water, sodium hydroxide, sodium disulfite, propyl parahydroxybenzoate, methyl parahydroxybenzoate.
Indications for use Ambrogeksala
The active substance Ambroxol has expectorant properties. The use of Ambrohexal helps to reduce the viscosity of sputum and facilitate its removal, while the amount of sputum does not increase, and the activity of the bronchi is suppressed. The drug is absorbed very quickly, the maximum concentration occurs in the lungs.
Ambrohexal is indicated for adults and children with bronchus and lung diseases (acute and chronic) associated with increased sputum formation, its difficult separation and advancement of bronchial secretion, namely, bronchial asthma, tracheitis, bronchiectasis, acute and chronic bronchitis. Ambrohexal is also used for rhinitis, sinusitis, pharyngitis and laryngitis. It provides quick and easy removal of mucus and sputum from the bronchi. The use of Ambrohexal has been shown as a prophylaxis of some complications that may arise as a result of operations on the respiratory organs, it is also used when there is a threat of premature birth, as a treatment and prevention of distress syndrome in premature babies.
According to the instructions to Ambrogeksalu, the drug is contraindicated to take with phenylketonuria, with ulcers of the gastrointestinal tact, in the first trimester of pregnancy. Under the supervision of a physician, a drug is prescribed for liver failure and during breastfeeding. Ambrohexal is combined with other drugs used to treat diseases of the bronchi. With simultaneous use of the drug has the properties to increase the concentration in the bronchial secretions and sputum in antibiotics (amoxicillin, erythromycin, cefuroxime). The simultaneous use of Ambrohexal and antitussive drugs with codeine is not recommended, sputum stagnation may occur.
Dosing and Administration Ambrohexal
According to the instructions to Ambroghexal, the drug in the form of tablets and capsules is taken orally, drinking water, after a meal. Tablets for adults and children over 12 years old are prescribed at a dosage of 30 mg (1 tablet) three times a day for the first 2-3 days. Further, the dosage is reduced to 1 tablet twice a day.
Children between the ages of 6 and 12 are prescribed half a tablet (15 mg) two to three times a day. Do not take the drug for more than 4-5 days without a doctor's prescription. During the entire treatment, the patient is recommended to drink more fluid to enhance the mucolytic effect.
The instructions to Ambroghexal indicated that the drug in the form of capsules is prescribed to adults and children over 12 years of age at a dosage of 1 capsule (75 mg) per day after eating in the morning or evening. Capsules are also not recommended to take more than 5 days without a doctor's prescription.
The solution for oral administration and the preparation of inhalations for adults and children over 12 years old is prescribed 4 ml (30 mg) 3 times a day for the first 2-3 days, then 4 ml once a day.
Children from 5 to 12 years old are prescribed 2 ml two or three times a day. Children from 2 to 5 years old - 1 ml three times a day. Children up to two years old - 1 ml 2 times a day only under the supervision of a physician. The solution should be dissolved in tea, water, juice or milk.
Inhalation with Ambrohexal solution for adults and children over 5 years old is carried out 1-2 times a day at a dose of 2-3 ml, for children under 5 years old - 2 ml Inhalation should be carried out using a special device.
The course of treatment can be prescribed only by the attending physician.
Side Effects of Ambrohexal
The use of Ambrohexal causes some side effects: nausea, weakness, constipation, vomiting, headache, skin rash, urticaria, itching, anaphylactic shock, rhinorrhea, dry mouth, diarrhea. In case of overdose, dyspepsia, vomiting, nausea, diarrhea can be observed. In this case, it is recommended to stop taking the drug, flush the stomach, causing vomiting, and eat more foods containing fats.
Ambrohexal is prescribed with caution to patients with a weakened cough reflex and with a poor ability to expectorate sputum, since the use of the drug can cause the accumulation of sputum in the bronchi. In patients with asthma, cough may be worse. It is not recommended to take the drug at night. People with impaired kidney and liver function should reduce the dosage of the drug or increase the interval between doses. Under the supervision of a physician, the drug is prescribed to patients with a stomach or intestinal ulcer due to possible exacerbation. Ambrohexal does not affect the ability to drive.
Analogs of Ambrohexal
Ambrohexal has quite a few analogues: Ambrobene, Ambroxol, Ambrolor, Deflegmin, Lazolvan, Lazolangin, Medox, Halixol.
Terms and conditions of storage
Ambrohexal is stored in a dark, dry place at room temperature.