Ambrobene is a mucolytic and expectorant drug.
Release form and composition
The drug is available in long-acting gelatin capsules. The contents of the capsules are white or light yellow granules. One capsule contains 75 mg of ambroxol hydrochloride. As excipients, hypromellose, microcrystalline cellulose, anhydrous colloidal silicon dioxide, methacrylic acid and ethyl acrylate copolymer are used.
Indications for use Ambrobene
Indications for use Ambrobene are acute and chronic diseases of the respiratory tract, which are accompanied by a violation of the formation and discharge of sputum.
According to the instructions to Ambrobene, the drug is contraindicated in case of hypersensitivity of the patient to the components of the drug. In addition, it is not prescribed to children under the age of 12 years and women in the first trimester of pregnancy.
With caution, the drug is used in patients with increased formation of sputum and impaired motor function of the bronchi, with an exacerbation of gastric ulcer and duodenal ulcer, as well as women in the 2nd and 3rd trimesters of pregnancy and lactation.
Ambrobene is prescribed with special care in patients with severe liver disease and impaired renal function. In this case, patients should take smaller doses of the drug or observe large intervals between doses.
Dosing and Administration Ambrobene
The drug should be taken after a meal, not chewing, but swallowing whole and washing it down with plenty of liquid. The duration of treatment depends on the course of the disease and is set individually. Adults and children over 12 years old are prescribed 1 capsule per day. Without prescription, the drug is not recommended to take longer than 4-5 days.
During treatment, it is recommended to drink plenty of liquids, since the mucolytic effect of Ambrobene is manifested when taking a large amount of fluid.
Side Effects Ambrobene
Unwanted effects from taking this drug are rarely observed. It can be:
- Allergic reactions - skin rash, urticaria, shortness of breath, itching, angioedema of the face;
- On the part of the digestive system - abdominal pain, diarrhea, nausea, vomiting, constipation;
- Others - weakness, headache, fever, rhinorrhea, dryness of the oral mucosa, exanthema, dysuria.
The drug Ambrobene should not be used simultaneously with antitussives, which make it difficult to remove sputum, as this can lead to stagnation of secretions due to the suppression of the cough reflex. Very rarely, severe skin reactions were observed when taking this drug: Lyell's syndrome and Stevens-Johnson syndrome. When signs of mucous membranes or skin appear, stop taking Ambrobene and seek medical help.
There is not enough data on the use of the drug during pregnancy, so its appointment in the 2 and 3 trimesters is possible only after a thorough assessment of the potential risk to the fetus and the expected benefits to the mother.
Joint intake of the drug with antibiotics leads to an increase in their concentration in sputum and bronchial secretions.
Analogues of the drug are drugs Ambroxol, Lasolvan, Mukobron, Medox, Remebroks and Halixol.
Terms and conditions of storage
According to the instructions to Ambrobene, the drug should be stored at temperatures up to 25 ° C, protected from children. The shelf life of the drug is 5 years.