Alpha D3-Teva is a drug that regulates phosphate and calcium metabolism in the body.
Release form and composition
Alpha D3-Teva is available in the form of capsules of 0.25 μg, 0.5 μg and 1 μg. It looks like oval soft capsules on a gelatin base of red-brown, pink or milky color. Each capsule contains an oily solution of light yellow color. Alpha D3-Teva active substance - alfacalcidol, excipients - propyl gallate, anhydrous citric acid, peanut oil, ethanol, alpha-tocopherol.
The drug is packaged in blisters or vials of 10 and 30 pieces.
Indications for use Alpha D3-Teva
The main active ingredient Alpha D3-Teva is alfacalcidol, it is in the body a precursor to the metabolite of vitamin D3. The drug helps to restore the balance of calcium and reduce the intensity of bone resorption, which reduces the frequency of fractures. Also, Alpha D3-Teva improves the absorption of calcium and phosphorus in the intestines, speeds up the process of reabsorption in the kidneys and helps saturate the bones with minerals. Regular use of Alpha D3-Teva helps to improve coordination of movements, reduces pain in bones and muscles associated with poor metabolism of phosphorus and calcium.
Indications for use Alpha D3-Teva are the following diseases:
- Rickets and osteomalacia associated with nutritional deficiencies or the problem of their absorption;
- Osteoporosis (postmenopausal, steroid, senile);
- Osteodystrophy in chronic renal failure;
- Hypophosphatemic rickets and osteomalacia;
- Pseudo-deficient osteomalacia and rickets;
- Hypoparathyroidism, hyperparathyroidism, pseudo-hyperparathyroidism;
- Renal acidosis and Fanconi syndrome.
According to the instructions to Alpha D3-Teva, the drug should not be taken in the presence of hypermagnesia, an excess of vitamin D3 in the body, with hypercalcemia, hyperphosphatemia, hypersensitivity to the components of the drug and women during breastfeeding. Not recommended for children under three years. With caution, the drug is prescribed to patients with renal insufficiency, with heart problems, in the active stage of pulmonary tuberculosis, atherosclerosis, nephrolithiasis and with an increased risk of hypercalcemia. During pregnancy, the drug can be taken only if the health benefits of women outweighs the possible risks to the child, but doctors note that defects in the development of the fetus are possible.
Dosage and administration Alpha D3-Teva
The drug is taken orally. The course of treatment can only be determined by the doctor depending on the severity of the disease. Adult patients for the treatment of rickets and osteomalacia associated with diseases of the stomach and intestines, with prolonged therapy and with exogenous lack of vitamin D3, are prescribed 1-3 μg per day. If the patient suffers from chronic renal failure or osteodystrophy, you should not take more than 2 micrograms. In Fanconi syndrome and renal acidosis, a daily dose of 2-6 μg is prescribed. In the presence of hypoparathyroidism, Alpha D3-Teva is prescribed at 2-4 μg, and in the case of osteomalacia or hypophosphatemic rickets, from 4 to 20 μg. Patients with osteoporosis (postmenopausal, steroid or senile) are prescribed a daily dose of 0.5-1 μg. The course of treatment should be started with the lowest dosages indicated in the instructions for Alpha D3-Teva, while monitoring the content of phosphorus and calcium in the blood should be carried out weekly. Increase the dosage should be gradually - no more than 0.5 mg per day until the normalization of biochemistry.
Side effects Alpha D3-Teva
The instructions to the Alpha D3-Teva indicated the following possible side effects:
- On the part of the digestive system: heartburn, abdominal pain, nausea, vomiting, dry mouth, epigastric pain, constipation or diarrhea;
- Since the cardiovascular system: tachycardia, high blood pressure;
- From the side of the central nervous system: fatigue, weakness, dizziness, drowsiness;
- Metabolism: hypercalcemia, increase in HDL in the blood;
- Very rarely there is an allergy in the form of pruritus and rash.
Patients with chronic renal failure and children should be monitored for phosphate and calcium: at the initial stage of treatment, Alpha D3-Teva - once a week, then once every 3-5 weeks. In case of renal failure, hyperphosphatemia should be corrected first.
In the early and late stages of treatment, it is necessary to monitor the calcium content in the body, especially if the patient does not have a serious defeat or if the calcium content in the blood is already elevated, and at the final stage of treatment - in the presence of signs of recovery of bone tissue. It is possible to determine the likelihood of developing hypercalcemia by the degree of bone demineralization, the functional ability of the kidneys and the dosage of Alpha D3-Teva. In the event of hypercalcemia and hypercalciuria, it is necessary to adjust the dosage of the drug, it takes about one week to restore the balance. After that, you can continue to take Alpha D3-Teva in the dosage half as much.
If a patient has a pronounced lesion of bone tissue, in contrast to patients with renal insufficiency, he can tolerate maximum doses of the drug without symptoms of hypercalcemia. Alpha D3-Teva can be taken simultaneously with phosphate-binding drugs to prevent the development of hyperphosphatemia in patients with lesions of the bone tissue of renal origin.
Children who take vitamin D for a long period of time may experience stunted growth. To prevent hypovitaminosis D, you need to adhere to a balanced diet.
Analogs Alpha D3-Teva
Analogs of Alpha D3-Teva are such drugs as Etalfa, Oksidevit, Van-Alpha.
Terms and conditions of storage
Alpha D3-Teva should be stored in a dark dry place inaccessible to children, at a temperature not higher than 25 ° C.