Acetylcysteine is a drug used to treat diseases of the respiratory system.
Release form and composition
Acetylcysteinum in the form of the white, possessing a lemon smell of the granules intended for preparation of solution, is let out in 4,7 mg of one-time packages.
One dose of granules (4.7 g) contains 206 mg of acetylcysteine and excipients - lactose, sodium carbonate, bicarbonate and saccharinate, anhydrous citric acid and citric flavoring additive.
Indications for use
In accordance with the instructions, Acetylcysteine is prescribed for the treatment of sinusitis, bronchitis, bronchitis, tracheitis, pneumonia, cystic fibrosis, laryngotracheitis, bronchiectasis, emphysema, atelectasis and lung abscess, sinusitis, purulent and catarrhal otitis.
The tool is used to remove viscous secretion from the airways in cases of postoperative or post-traumatic conditions, in preparing the patient for bronchography, bronchoscopy and aspiration drainage.
Acetylcysteine is also used to wash the nasal passages, middle ear, abscesses and maxillary sinuses.
The use of Acetylcysteine is contraindicated during pregnancy, hypersensitivity to the components of the tool and during breastfeeding.
With caution, the drug is prescribed in cases of arterial hypotension, duodenal ulcer and stomach ulcers, hemoptysis, asthma, esophageal varicose veins, pulmonary hemorrhage, hepatic or renal failure, phenylketonuria, and adrenal gland disease.
Dosing and Administration
The medication in the form of tablets, granules or capsules is taken orally by adults two or three times a day, 200 mg. Children from 6 to 14 years old are prescribed water-soluble granules twice a day at a dose of 200 mg, patients from 2 to 6 years old — twice a day, 200 mg or three times a day, 100 mg, children under two years old — 100 mg Acetylcysteine twice a day.
The drug in the form of a solution can be applied topically, inhalation, parenterally and intratracheally.
For inhalation use 20 ml of 10% or 2-5 ml of 20% solution of the drug from two to four times a day for 5-10 days. The duration of the procedure is on average 15-20 minutes.
In cases of parenteral administration, Acetylcysteine is diluted with 0.9% sodium chloride solution before use and used intramuscularly or intravenously. The dosage of the agent for adults is 300 mg, and for children 6-14 years old - 150 mg once or twice a day for no more than ten days.
When using Acetylcysteine in some cases causes rhinorrhea, fever, bronchospasm, drowsiness, allergic reactions, stomatitis, vomiting, a feeling of fullness in the stomach and nausea.
During intramuscular administration of the drug, there may be a burning sensation at the injection site, and during aerosol therapy - rhinorrhea, stomatitis, irritation of the respiratory tract and reflex cough.
In cases of use of Acetylcysteinum to patients with a diabetes mellitus it is necessary to know that each granule of means contains sucrose. For patients with broncho-obstructive syndrome, the drug is prescribed in combination with bronchodilators.
Synonyms of the drug are medicines Acestin, ACC, Mukoneks, N-AC-ratiopharm and Fluimucil.
Analogues of acetylcysteine are drugs such as:
Terms and conditions of storage
Acetylcysteine, according to the instructions, should be stored in a dry place inaccessible to children and light, at a temperature not exceeding 30 ° C.
Release the drug from pharmacies by prescription. The shelf life of the drug is three years. After the expiration date, acetylcysteine must be disposed of.